Literature DB >> 8765161

The nematode Caenorhabditis elegans is up to 39 times more sensitive to gamma radiation generated from 137Cs than from 60Co.

P Hartman1, P Goldstein, M Algarra, D Hubbard, J Mabery.   

Abstract

Survival after gamma irradiation (generated from either a 137Cs or 60Co source) was determined for two strains of the nematode Caenorhabditis elegans. Animals were between 1.3 and 39 times more sensitive to cesium than to cobalt. The magnitude of this differential sensitivity was dependent upon the strain, developmental stage and sex tested. Several control experiments eliminated trivial explanations for this difference. Since cobalt- and cesium-generated gamma particles have nearly identical energy depositions, the differential sensitivity likely reflects different mechanisms of processing the slightly different spectra of DNA damage induced by these two radiations. Sex-specific differences in radiation sensitivity were also noted and were likely due to the fact that males possess a single X chromosome rather than two, as do hermaphrodites.

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Year:  1996        PMID: 8765161     DOI: 10.1016/0921-8777(96)00012-2

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  5 in total

1.  Hyper-resistance of meiotic cells to radiation due to a strong expression of a single recA-like gene in Caenorhabditis elegans.

Authors:  T Takanami; A Mori; H Takahashi; A Higashitani
Journal:  Nucleic Acids Res       Date:  2000-11-01       Impact factor: 16.971

2.  A Caenorhabditis elegans tissue model of radiation-induced reproductive cell death.

Authors:  J B Weidhaas; D M Eisenmann; J M Holub; S V Nallur
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-20       Impact factor: 11.205

3.  Methodological considerations for mutagen exposure in C. elegans.

Authors:  Zebulin Kessler; Judith Yanowitz
Journal:  Methods       Date:  2014-04-21       Impact factor: 3.608

4.  Genome integrity is regulated by the Caenorhabditis elegans Rad51D homolog rfs-1.

Authors:  Judith L Yanowitz
Journal:  Genetics       Date:  2008-05-05       Impact factor: 4.562

5.  Effects of 60Co γ Irradiation on the Reproductive Function of Caenorhabditis elegans.

Authors:  Fengmei Cui; Nan Ma; Xiaojing Han; Na Chen; Yue Xi; Weiye Yuan; Yufan Xu; Jianfang Han; Xiaoyan Xu; Yu Tu
Journal:  Dose Response       Date:  2019-01-10       Impact factor: 2.658

  5 in total

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