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Literature DB >> 8764942

Chromosome 6 trisomy as sole anomaly in a primary Merkel cell carcinoma.

Abstract

We present a case of Merkel cell carcinoma of the thigh diagnosed by conventional histology, immunohistochemistry, electron microscopy and cytogenetics. A unique chromosome 6 trisomy characterized this primary neoplasm, as confirmed by FISH study. The role of chromosome analysis and interphase cytogenetics is emphasized as an adjunct in the subtyping of tumours and their prognostic evaluation.

Entities: Disease

Mesh：

Substances：
Keratins

Year: 1996 PMID： 8764942 DOI： 10.1007/bf00196706

Source DB: PubMed Journal: Virchows Arch ISSN： 0945-6317 Impact factor: 4.064

23 in total

1. Primary neuroendocrine (Merkel cell?) carcinoma of the skin. II. An immunocytochemical study of 21 cases.

Authors: R K Sibley; D Dahl
Journal: Am J Surg Pathol Date: 1985-02 Impact factor: 6.394

2. Primary neuroendocrine (Merkel cell?) carcinoma of the skin. I. A clinicopathologic and ultrastructural study of 43 cases.

Authors: R K Sibley; L P Dehner; J Rosai
Journal: Am J Surg Pathol Date: 1985-02 Impact factor: 6.394

3. Involvement of chromosome 22 in a Merkel cell carcinoma in a patient with a previous meningioma.

Authors: F Shabtai; A Sternberg; D Klar; R Reiss; I Halbrecht
Journal: Cancer Genet Cytogenet Date: 1989-03

4. [Neuroendocrine tumor of the skin. Demonstration of chromosome abnormalities in tumor cells].

Authors: C Hopfner; J R Teyssier; D Eychenne; F Lesaunier; F Nollez; J J Adnet
Journal: Presse Med Date: 1987-04-25 Impact factor: 1.228

5. Short communication: deletion 7q, trisomy 6 and 11 in a case of Merkel-cell carcinoma.

Authors: F Sandbrink; L Müller; H H Fiebig; G Kovacs
Journal: Cancer Genet Cytogenet Date: 1988-07-15

6. Chromosomal evolution in a Merkel cell carcinoma.

Authors: B Schlegelberger; H Bartels; W Sterry
Journal: Cancer Genet Cytogenet Date: 1994-07-01

7. Application of long-term collagenase disaggregation for the cytogenetic analysis of human solid tumors.

Authors: J Limon; P Dal Cin; A A Sandberg
Journal: Cancer Genet Cytogenet Date: 1986-12

8. Establishment and characterization of a neuroendocrine skin carcinoma cell line.

Authors: S T Rosen; V E Gould; H R Salwen; C V Herst; M M Le Beau; I Lee; K Bauer; R J Marder; R Andersen; M S Kies
Journal: Lab Invest Date: 1987-03 Impact factor: 5.662

9. Neuroendocrine carcinoma within lymph nodes in the absence of a primary tumor, with special reference to Merkel cell carcinoma.

Authors: V Eusebi; C Capella; A Cossu; J Rosai
Journal: Am J Surg Pathol Date: 1992-07 Impact factor: 6.394