Literature DB >> 8764095

Evidence for a phosphorylation site in cytomegalovirus glycoprotein gB.

N Norais1, J A Hall, L Gross, D Tang, S Kaur, S H Chamberlain, R L Burke, F Marcus.   

Abstract

As part of our vaccine program, we have purified a recombinant form of human cytomegalovirus glycoprotein B that is able to induce high titers of virus-neutralizing antibodies. The isolated protein was found to be phosphorylated at a serine residue in position -7 from the C terminus of the protein. The corresponding synthetic peptide, HLKDSDEEENV, was an efficient in vitro substrate of casein kinase II.

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Year:  1996        PMID: 8764095      PMCID: PMC190541     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  19 in total

1.  Congenital cytomegalovirus disease--20 years is long enough.

Authors:  M D Yow; G J Demmler
Journal:  N Engl J Med       Date:  1992-03-05       Impact factor: 91.245

2.  Appendix 5. Nomenclature for peptide fragment ions (positive ions).

Authors:  K Biemann
Journal:  Methods Enzymol       Date:  1990       Impact factor: 1.600

Review 3.  A recombinant subunit vaccine approach to HCMV vaccine development.

Authors:  R R Spaete
Journal:  Transplant Proc       Date:  1991-06       Impact factor: 1.066

4.  Substrate specificity determinants for casein kinase II as deduced from studies with synthetic peptides.

Authors:  E A Kuenzel; J A Mulligan; J Sommercorn; E G Krebs
Journal:  J Biol Chem       Date:  1987-07-05       Impact factor: 5.157

5.  Protein sequencing by tandem mass spectrometry.

Authors:  D F Hunt; J R Yates; J Shabanowitz; S Winston; C R Hauer
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

6.  High-sensitivity peptide mapping of triosephosphate isomerase: a comparison of high-performance liquid chromatography with two-dimensional thin-layer methods.

Authors:  B Oray; M Jahani; R W Gracy
Journal:  Anal Biochem       Date:  1982-09-01       Impact factor: 3.365

7.  Nucleotide sequence of the gene encoding infectious laryngotracheitis virus glycoprotein B.

Authors:  K Kongsuwan; C T Prideaux; M A Johnson; M Sheppard; K J Fahey
Journal:  Virology       Date:  1991-09       Impact factor: 3.616

8.  Glycoprotein B of human cytomegalovirus promotes virion penetration into cells, transmission of infection from cell to cell, and fusion of infected cells.

Authors:  D Navarro; P Paz; S Tugizov; K Topp; J La Vail; L Pereira
Journal:  Virology       Date:  1993-11       Impact factor: 3.616

9.  Identification of the murine cytomegalovirus glycoprotein B gene and its expression by recombinant vaccinia virus.

Authors:  M Rapp; M Messerle; B Bühler; M Tannheimer; G M Keil; U H Koszinowski
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

10.  Mutated forms of human cytomegalovirus glycoprotein B are impaired in inducing syncytium formation.

Authors:  S Tugizov; Y Wang; I Qadri; D Navarro; E Maidji; L Pereira
Journal:  Virology       Date:  1995-06-01       Impact factor: 3.616

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  10 in total

1.  Phosphorylation of simian cytomegalovirus assembly protein precursor (pAPNG.5) and proteinase precursor (pAPNG1): multiple attachment sites identified, including two adjacent serines in a casein kinase II consensus sequence.

Authors:  S M Plafker; A S Woods; W Gibson
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

2.  An acidic cluster in the cytosolic domain of human cytomegalovirus glycoprotein B is a signal for endocytosis from the plasma membrane.

Authors:  S Tugizov; E Maidji; J Xiao; L Pereira
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

3.  Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production.

Authors:  Colin M Crump; Chien-Hui Hung; Laurel Thomas; Lei Wan; Gary Thomas
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

4.  The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic.

Authors:  Gregory K Scott; Feng Gu; Colin M Crump; Laurel Thomas; Lei Wan; Yang Xiang; Gary Thomas
Journal:  EMBO J       Date:  2003-12-01       Impact factor: 11.598

5.  Human cytomegalovirus glycoprotein B contains autonomous determinants for vectorial targeting to apical membranes of polarized epithelial cells.

Authors:  S Tugizov; E Maidji; J Xiao; Z Zheng; L Pereira
Journal:  J Virol       Date:  1998-09       Impact factor: 5.103

6.  Deletion of gpUL132, a structural component of human cytomegalovirus, results in impaired virus replication in fibroblasts.

Authors:  Simone Spaderna; Barbara Kropff; Yvonne Ködel; Siyuan Shen; Scott Coley; Shan Lu; William Britt; Michael Mach
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

7.  Intracellular formation and processing of the heterotrimeric gH-gL-gO (gCIII) glycoprotein envelope complex of human cytomegalovirus.

Authors:  M T Huber; T Compton
Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

8.  Steady-state plasma membrane expression of human cytomegalovirus gB is determined by the phosphorylation state of Ser900.

Authors:  K N Fish; C Soderberg-Naucler; J A Nelson
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

9.  Regulation of endosome sorting by a specific PP2A isoform.

Authors:  S S Molloy; L Thomas; C Kamibayashi; M C Mumby; G Thomas
Journal:  J Cell Biol       Date:  1998-09-21       Impact factor: 10.539

10.  Lack of autoantibody production associated with cytomegalovirus infection.

Authors:  Beth C Marshall; Richard A McPherson; Eric Greidinger; Robert Hoffman; Stuart P Adler
Journal:  Arthritis Res       Date:  2002-06-20
  10 in total

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