Literature DB >> 8762001

Nitric oxide synthase levels in obese Zucker rats.

J E Morley1, M B Mattammal.   

Abstract

Nitric oxide has been demonstrated to play a role in the modulation of food intake. The Zucker fatty rat is an autosomal recessive genetic model of obesity. We measured nitric oxide synthase (NOS) in the hypothalamus and fundus of the stomach in Zucker (fa/fa) rats and their lean littermate controls (fa/?). NOS activity was decreased in both the hypothalamus and the fundus of the Zucker (fa/fa) rats compared to the littermate controls.

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Year:  1996        PMID： 8762001     DOI： 10.1016/0304-3940(96)12622-7

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  6 in total

1.  The mitochondrial function of the cerebral vasculature in insulin-resistant Zucker obese rats.

Authors:  Ivan Merdzo; Ibolya Rutkai; Tunde Tokes; Venkata N L R Sure; Prasad V G Katakam; David W Busija
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-02-12       Impact factor: 4.733

2.  Systemic but not central nervous system nitric oxide synthase inhibition exacerbates the hypertensive effects of chronic melanocortin-3/4 receptor activation.

Authors:  Jussara M do Carmo; Mirian Bassi; Alexandre A da Silva; John E Hall
Journal:  Hypertension       Date:  2011-01-24       Impact factor: 10.190

3.  Increased neuronal nitric oxide synthase dimerisation is involved in rat and human pancreatic beta cell hyperactivity in obesity.

Authors:  K Mezghenna; P Pomiès; A Chalançon; F Castex; J Leroy; N Niclauss; B Nadal; L Cambier; C Cazevieille; P Petit; R Gomis; T Berney; R Gross; A D Lajoix
Journal:  Diabetologia       Date:  2011-08-18       Impact factor: 10.122

4.  Effects of obesity on the pharmacodynamics of nitroglycerin in conscious rats.

Authors:  Ellen Q Wang; Ho-Leung Fung
Journal:  AAPS PharmSci       Date:  2002

5.  Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor.

Authors:  Swasti Tiwari; Nikhil Sharma; Pritmohinder S Gill; Peter Igarashi; C Ronald Kahn; James B Wade; Carolyn M A Ecelbarger
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-18       Impact factor: 11.205

6.  Increase of NADPH-diaphorase expression in hypothalamus of stat4 knockout mice.

Authors:  Mee Sook Hong; Jeong Yoon Song; Dong Hwan Yun; Jeong-Je Cho; Joo-Ho Chung
Journal:  Korean J Physiol Pharmacol       Date:  2009-10-31       Impact factor: 2.016
  6 in total

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