| Literature DB >> 8757802 |
G Parkinson1, C Wilson, A Gunasekera, Y W Ebright, R H Ebright, R E Ebright, H M Berman.
Abstract
The crystallographic structure of the CAP-DNA complex at 3.0 A resolution has been reported previously. For technical reasons, the reported structure had been determined using a gapped DNA molecule lacking two phosphates important for CAP-DNA interaction. In this work, we report the crystallographic structure of the CAP-DNA complex at 2.5 A resolution using a DNA molecule having all phosphates important for CAP-DNA interaction. The present resolution permits unambiguous identification of amino acid-base and amino acid-phosphate hydrogen bonded contacts in the CAP-DNA complex. In addition, the present resolution permits accurate definition of the kinked DNA conformation in the CAP-DNA complex.Entities:
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Year: 1996 PMID: 8757802 DOI: 10.1006/jmbi.1996.0409
Source DB: PubMed Journal: J Mol Biol ISSN: 0022-2836 Impact factor: 5.469