Literature DB >> 8757128

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.

T Bouwmeester1, S Kim, Y Sasai, B Lu, E M De Robertis.   

Abstract

An abundant cDNA enriched in Spemann's organizer, cerberus, was isolated by differential screening. It encodes a secreted protein that is expressed in the anterior endomesoderm. Microinjection of cerberus mRNA into Xenopus embryos induces ectopic heads, and duplicated hearts and livers. The results suggest a role for a molecule expressed in the anterior endoderm in the induction of head structures in the vertebrate embryo.

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Year:  1996        PMID： 8757128     DOI： 10.1038/382595a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  124 in total

1.  Inhibition of Wnt activity induces heart formation from posterior mesoderm.

Authors:  M J Marvin; G Di Rocco; A Gardiner; S M Bush; A B Lassar
Journal:  Genes Dev       Date:  2001-02-01       Impact factor: 11.361

Review 2.  The establishment of Spemann's organizer and patterning of the vertebrate embryo.

Authors:  E M De Robertis; J Larraín; M Oelgeschläger; O Wessely
Journal:  Nat Rev Genet       Date:  2000-12       Impact factor: 53.242

3.  Axis determination by inhibition of Wnt signaling in Xenopus.

Authors:  K Itoh; S Y Sokol
Journal:  Genes Dev       Date:  1999-09-01       Impact factor: 11.361

4.  Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif.

Authors:  S Germain; M Howell; G M Esslemont; C S Hill
Journal:  Genes Dev       Date:  2000-02-15       Impact factor: 11.361

Review 5.  The Spemann organizer and embryonic head induction.

Authors:  C Niehrs
Journal:  EMBO J       Date:  2001-02-15       Impact factor: 11.598

Review 6.  Evolution of vertebrate forebrain development: how many different mechanisms?

Authors:  A C Foley; C D Stern
Journal:  J Anat       Date:  2001 Jul-Aug       Impact factor: 2.610

7.  Conservation of Pax 6 function and upstream activation by Notch signaling in eye development of frogs and flies.

Authors:  Yasuko Onuma; Shuji Takahashi; Makoto Asashima; Shoichiro Kurata; Walter J Gehring
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-12       Impact factor: 11.205

8.  Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus.

Authors:  O Wessely; E Agius; M Oelgeschläger; E M Pera; E M De Robertis
Journal:  Dev Biol       Date:  2001-06-01       Impact factor: 3.582

9.  Choice of either beta-catenin or Groucho/TLE as a co-factor for Xtcf-3 determines dorsal-ventral cell fate of diencephalon during Xenopus development.

Authors:  Saori Tsuji; Chikara Hashimoto
Journal:  Dev Genes Evol       Date:  2005-03-04       Impact factor: 0.900

10.  Hypoblast controls mesoderm generation and axial patterning in the gastrulating rabbit embryo.

Authors:  Jan Idkowiak; Gunnar Weisheit; Juliane Plitzner; Christoph Viebahn
Journal:  Dev Genes Evol       Date:  2004-10-06       Impact factor: 0.900
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