Literature DB >> 875643

Potential anticancer agents. IV. Constituents of Jacaranda caucana Pittier (Bignoniaceae).

M Ogura, G A Cordell, R Farnsworth.   

Abstract

An aqueous ethanol extract of Jacaranda caucana Pittier (Bignoniaceae) showed in vivo antitumor activity against the P-388 lymphocytic leukemia system. Fractionation, accompanied by monitoring for biological activity, afforded a novel phytoquinoid derivative jacaranone, which exhibited both in vivo antitumor and in vitro cytotoxic activity. beta-Sitosterol, betulinic acid, ursolic acid, 2alpha-hydroxyursolic acid, 2alpha,3alpha-dihydroxyurs-12-en-28-oic acid and a new triterpene acid, jacarandic acid, were also isolated. The structure elucidation of jacarandic acid is described.

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Year:  1977        PMID： 875643

Source DB:  PubMed          Journal:  Lloydia        ISSN： 0024-5461


  3 in total

1.  Lupane triterpenoids from Acacia mellifera with cytotoxic activity.

Authors:  Charles Mutai; Dennis Abatis; Constantinos Vagias; Dimitri Moreau; Christos Roussakis; Vassilios Roussis
Journal:  Molecules       Date:  2007-05-15       Impact factor: 4.411

2.  Antioxidant and cytotoxic activity of hydroethanolic extract from Jacaranda decurrens leaves.

Authors:  Junior Cesar Casagrande; Luis Fernando Benitez Macorini; Katia Avila Antunes; Uilson Pereira Dos Santos; Jaqueline Ferreira Campos; Nelson Miguel Dias-Júnior; Andréia Sangalli; Claudia Andrea Lima Cardoso; Maria do Carmo Vieira; Luiza Antas Rabelo; Edgar Julian Paredes-Gamero; Edson Lucas Dos Santos; Kely de Picoli Souza
Journal:  PLoS One       Date:  2014-11-17       Impact factor: 3.240

3.  Jacaranone Derivatives with Antiproliferative Activity from Crepis pulchra and Relevance of This Group of Plant Metabolites.

Authors:  Csilla Zsuzsanna Dávid; Norbert Kúsz; Gyula Pinke; Ágnes Kulmány; István Zupkó; Judit Hohmann; Andrea Vasas
Journal:  Plants (Basel)       Date:  2022-03-16
  3 in total

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