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Literature DB >> 875244

Value of prophylactic oophorectomy in advanced breast cancer with parasternal lymph nodes metastasis.

Abstract

In order to improve the poor prognosis of advanced breast cancer cases with positive parasternal lymph nodes metastasis, prophylactic oophorectomy was performed in 25 unselected cases. In a retrospective study on the breast cancer cases operated on from 1958 to 1969, comparison of eight advanced breast cancer cases with positive parasternal lymph nodes metastasis after radical mastectomy of Halsted type and parasternal lymph nodes dissection with, and 17 cases without prophylactic bilateral oophorectomy was made with respect to the survival rate, the survival time pattern by Mantel-Haenszel's procedure in their entirety and the recurrence rate. These results suggest the effectiveness of prophylactic oophorectomy for the advanced breast cancer.

Entities: Disease

Mesh：

Year: 1977 PMID： 875244 DOI： 10.1007/bf02469386

Source DB: PubMed Journal: Jpn J Surg ISSN： 0047-1909

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References

13 in total

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Journal: Surg Gynecol Obstet Date: 1953-10

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Authors: N TREVES; J A FINKBEINER
Journal: Cancer Date: 1958 Mar-Apr Impact factor: 6.860

Value of prophylactic oophorectomy in advanced breast cancer with parasternal lymph nodes metastasis.

1. Carcinoma of the breast; results, evaluation of X-radiation, and relation of age and surgical castration to length of survival.

2. Glandular metastases in carcinoma of the breast; results of a more radical operation.

3. Artificial menopause as an adjunct to radical treatment of breast cancer.

4. Radical mastectomy in continuity with en bloc resection of the internal mammary lymph-node chain; a new procedure for primary operable cancer of the breast.

5. The prediction of hormonal dependency of mammary cancer.

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8. Results of a clinical trial concerning the worth of prophylactic oophorectomy for breast carcinoma.

9. Evaluation of survival data and two new rank order statistics arising in its consideration.

10. An evaluation of therapeutic surgical castration in the treatment of metastatic, recurrent, and primary inoperable mammary carcinoma in women; an analysis of 191 patients.