Literature DB >> 8751946

Transforming growth factor beta is protective in host resistance against Listeria monocytogenes infection in mice.

A Nakane1, M Asano, S Sasaki, S Nishikawa, T Miura, M Kohanawa, T Minagawa.   

Abstract

The role of transforming growth factor beta (TGF-beta) in host resistance against Listeria monocytogenes infection was studied with mice. The constitutive expression of TGF-beta 1 mRNA was observed in the spleens and livers of mice before and after infection. Injecting the mice with anti-TGF-beta 1 peptide serum resulted in diminished antilisterial resistance, whereas the administration of human platelet-derived TGF-beta 1 enhanced the resistance. Moreover, mice were protected against lethal infection when treated with TGF-beta 1. These results suggest the TGF-beta 1 might be involved in antilisterial resistance. On the other hand, injecting the mice with TGF-beta 1 resulted in a decrease in the titers of endogenous gamma interferon, tumor necrosis factor alpha, and interleukin-6, which are crucial in antilisterial resistance, in sera and in extracts of spleen and liver. Thus, a complicated mechanism might be involved in the role of TGF-beta 1 in host resistance against L. monocytogenes infection.

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Year:  1996        PMID： 8751946      PMCID： PMC174310          DOI： 10.1128/iai.64.9.3901-3904.1996

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  25 in total

1.  Deactivation of macrophages by transforming growth factor-beta.

Authors:  S Tsunawaki; M Sporn; A Ding; C Nathan
Journal:  Nature       Date:  1988-07-21       Impact factor: 49.962

2.  Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection.

Authors:  A Nakane; T Minagawa; K Kato
Journal:  Infect Immun       Date:  1988-10       Impact factor: 3.441

3.  Antibodies to peptide determinants in transforming growth factor beta and their applications.

Authors:  K C Flanders; A B Roberts; N Ling; B E Fleurdelys; M B Sporn
Journal:  Biochemistry       Date:  1988-01-26       Impact factor: 3.162

4.  Endogenous interleukin-4, but not interleukin-10, is involved in suppression of host resistance against Listeria monocytogenes infection in interferon-depleted mice.

Authors:  A Nakane; S Nishikawa; S Sasaki; T Miura; M Asano; M Kohanawa; K Ishiwata; T Minagawa
Journal:  Infect Immun       Date:  1996-04       Impact factor: 3.441

5.  Production of tumor necrosis factor during murine listeriosis.

Authors:  E A Havell
Journal:  J Immunol       Date:  1987-12-15       Impact factor: 5.422

6.  Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1.

Authors:  W A Border; S Okuda; L R Languino; M B Sporn; E Ruoslahti
Journal:  Nature       Date:  1990-07-26       Impact factor: 49.962

7.  Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection.

Authors:  N A Buchmeier; R D Schreiber
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

8.  Inhibition of cytokine production by cyclosporin A and transforming growth factor beta.

Authors:  T Espevik; I S Figari; M R Shalaby; G A Lackides; G D Lewis; H M Shepard; M A Palladino
Journal:  J Exp Med       Date:  1987-08-01       Impact factor: 14.307

9.  Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

Authors:  J H Kehrl; L M Wakefield; A B Roberts; S Jakowlew; M Alvarez-Mon; R Derynck; M B Sporn; A S Fauci
Journal:  J Exp Med       Date:  1986-05-01       Impact factor: 14.307

10.  Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha.

Authors:  G E Ranges; I S Figari; T Espevik; M A Palladino
Journal:  J Exp Med       Date:  1987-10-01       Impact factor: 14.307
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  6 in total

1.  Ambiguous role of interleukin-12 in Yersinia enterocolitica infection in susceptible and resistant mouse strains.

Authors:  E Bohn; E Schmitt; C Bielfeldt; A Noll; R Schulte; I B Autenrieth
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

2.  A physical/psychological and biological stress combine to enhance endoplasmic reticulum stress.

Authors:  Tapan Kumar Mondal; Rebecca T Emeny; Donghong Gao; Jeffrey G Ault; Jane Kasten-Jolly; David A Lawrence
Journal:  Toxicol Appl Pharmacol       Date:  2015-09-21       Impact factor: 4.219

3.  Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi.

Authors:  N Gomez-Escobar; W F Gregory; R M Maizels
Journal:  Infect Immun       Date:  2000-11       Impact factor: 3.441

4.  Effect of transforming growth factor beta on experimental Salmonella typhimurium infection in mice.

Authors:  M Galdiero; A Marcatili; G Cipollaro de l'Ero; I Nuzzo; C Bentivoglio; M Galdiero; C Romano Carratelli
Journal:  Infect Immun       Date:  1999-03       Impact factor: 3.441

5.  Listeria monocytogenes impairs SUMOylation for efficient infection.

Authors:  David Ribet; Mélanie Hamon; Edith Gouin; Marie-Anne Nahori; Francis Impens; Hélène Neyret-Kahn; Kris Gevaert; Joël Vandekerckhove; Anne Dejean; Pascale Cossart
Journal:  Nature       Date:  2010-04-22       Impact factor: 49.962

Review 6.  Type I Natural Killer T Cells as Key Regulators of the Immune Response to Infectious Diseases.

Authors:  Nicolás M S Gálvez; Karen Bohmwald; Gaspar A Pacheco; Catalina A Andrade; Leandro J Carreño; Alexis M Kalergis
Journal:  Clin Microbiol Rev       Date:  2020-12-23       Impact factor: 26.132
  6 in total

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