Literature DB >> 8751137

Molecular mechanisms of virus-induced carcinogenesis: the interaction of viral factors with cellular tumor suppressor proteins.

F Hoppe-Seyler1, K Butz.   

Abstract

Accumulating evidence indicates that tumor viruses represent a major etiological factor in a significant portion of human cancers. These cancers include human papillomavirus induced anogenital cancers, hepatitis B and C virus associated hepatocellular carcinomas, nasopharyngeal carcinomas and lymphomas linked to Epstein-Barr virus infection, and human T cell leukemia virus associated adult T cell leukemias. This review summarizes the recent progress made in understanding the molecular mechanisms of viral carcinogenesis, with a particular focus on the interaction of viral factors with cellular tumor suppressor proteins. The functional inactivation of tumor suppressor proteins may represent a common strategy by which several tumor viruses contribute to malignant cell transformation.

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Year:  1995        PMID： 8751137     DOI： 10.1007/bf00195138

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  93 in total

1.  Primary hepatocellular carcinoma.

Authors:  J R Wands; H E Blum
Journal:  N Engl J Med       Date:  1991-09-05       Impact factor: 91.245

2.  Inhibition of p53-mediated transactivation by E6 of type 1, but not type 5, 8, or 47, human papillomavirus of cutaneous origin.

Authors:  T Kiyono; A Hiraiwa; S Ishii; T Takahashi; M Ishibashi
Journal:  J Virol       Date:  1994-07       Impact factor: 5.103

Review 3.  Interaction of adenoviral proteins with pRB and p53.

Authors:  E Moran
Journal:  FASEB J       Date:  1993-07       Impact factor: 5.191

4.  Risk factors for hepatocellular carcinoma among patients with chronic liver disease.

Authors:  H Tsukuma; T Hiyama; S Tanaka; M Nakao; T Yabuuchi; T Kitamura; K Nakanishi; I Fujimoto; A Inoue; H Yamazaki
Journal:  N Engl J Med       Date:  1993-06-24       Impact factor: 91.245

Review 5.  Viruses in human cancers.

Authors:  H zur Hausen
Journal:  Science       Date:  1991-11-22       Impact factor: 47.728

6.  p53 status and the efficacy of cancer therapy in vivo.

Authors:  S W Lowe; S Bodis; A McClatchey; L Remington; H E Ruley; D E Fisher; D E Housman; T Jacks
Journal:  Science       Date:  1994-11-04       Impact factor: 47.728

7.  Protein domains governing interactions between E2F, the retinoblastoma gene product, and human papillomavirus type 16 E7 protein.

Authors:  P S Huang; D R Patrick; G Edwards; P J Goodhart; H E Huber; L Miles; V M Garsky; A Oliff; D C Heimbrook
Journal:  Mol Cell Biol       Date:  1993-02       Impact factor: 4.272

Review 8.  Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

Authors:  M S Greenblatt; W P Bennett; M Hollstein; C C Harris
Journal:  Cancer Res       Date:  1994-09-15       Impact factor: 12.701

9.  Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein.

Authors:  J J Chen; C E Reid; V Band; E J Androphy
Journal:  Science       Date:  1995-07-28       Impact factor: 47.728

10.  HPV16 E7 oncoprotein deregulates B-myb expression: correlation with targeting of p107/E2F complexes.

Authors:  E W Lam; J D Morris; R Davies; T Crook; R J Watson; K H Vousden
Journal:  EMBO J       Date:  1994-02-15       Impact factor: 11.598
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  7 in total

1.  MDM2 is a target of simian virus 40 in cellular transformation and during lytic infection.

Authors:  W Henning; G Rohaly; T Kolzau; U Knippschild; H Maacke; W Deppert
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

2.  Specific chromosomal imbalances in human papillomavirus-transfected cells during progression toward immortality.

Authors:  S Solinas-Toldo; M Dürst; P Lichter
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-15       Impact factor: 11.205

3.  The impact of GSTM1/GSTT1 polymorphism for the risk of oral cancer.

Authors:  Maximilian Krüger; Andreas Max Pabst; Benjamin Mahmoodi; Burkhard Becker; Peer Wolfgang Kämmerer; Felix Peter Koch
Journal:  Clin Oral Investig       Date:  2015-01-18       Impact factor: 3.573

4.  The full-length isoform of human papillomavirus 16 E6 and its splice variant E6* bind to different sites on the procaspase 8 death effector domain.

Authors:  Sandy S Tungteakkhun; Maria Filippova; Nadja Fodor; Penelope J Duerksen-Hughes
Journal:  J Virol       Date:  2009-11-11       Impact factor: 5.103

Review 5.  Immunosuppressive therapy and malignancy in organ transplant recipients: a systematic review.

Authors:  Alex Gutierrez-Dalmau; Josep M Campistol
Journal:  Drugs       Date:  2007       Impact factor: 9.546

6.  Loss of heterozygosity for defined regions on chromosomes 3, 11 and 17 in carcinomas of the uterine cervix.

Authors:  A M Kersemaekers; J Hermans; G J Fleuren; M J van de Vijver
Journal:  Br J Cancer       Date:  1998       Impact factor: 7.640

7.  The Oncolytic Virotherapy Era in Cancer Management: Prospects of Applying H-1 Parvovirus to Treat Blood and Solid Cancers.

Authors:  Assia L Angelova; Mathias Witzens-Harig; Angel S Galabov; Jean Rommelaere
Journal:  Front Oncol       Date:  2017-05-12       Impact factor: 6.244
  7 in total

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