Literature DB >> 8751050

Origins of simian immunodeficiency virus infection in macaques at the New England Regional Primate Research Center.

K G Mansfield1, N W Lerch, M B Gardner, A A Lackner.   

Abstract

A cohort of rhesus macaques (Macaca mulatta), obtained from the California Regional Primate Research Center (CRPRC) and necropsied in 1970-72 with lesions suggestive of simian immunodeficiency virus (SIV) infection, was identified at the New England Regional Primate Research Center (NERPRC). Polymerase chain reaction (PCR), DNA sequence analysis, and in situ hybridization were used to confirm the presence of SIV nucleic acids. This represents the earliest case of SIV infection at the NERPRC and suggests a common source for present day SIV isolates.

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Year:  1995        PMID： 8751050     DOI： 10.1111/j.1600-0684.1995.tb00156.x

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  33 in total

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Review 8.  Animal models for HIV/AIDS research.

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Review 9.  Virus-host interaction in the simian immunodeficiency virus-infected brain.

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10.  Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2.

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