Literature DB >> 8750871

Localization of mRNA for phosphatidylinositol 3-kinase in brain of developing and mature rats.

Y Ito1, K Goto, H Kondo.   

Abstract

In the adult brain, the gene expression for phosphatidylinositol 3-kinase was weak in almost all neurons with relatively high levels in the olfactory bulb, hippocampus, and cerebellum. On the embryonic days high levels of the gene expression were found throughout the entire neuraxis, then decreased gradually to adult levels during postnatal development. The present finding suggests that phosphatidylinositol 3-kinase may contribute not only to neurogenesis but also to some important physiological roles in differentiating and mature neurons.

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Year:  1995        PMID: 8750871     DOI: 10.1016/0169-328x(95)00153-j

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN: 0169-328X


  5 in total

1.  A role for nuclear PTEN in neuronal differentiation.

Authors:  M B Lachyankar; N Sultana; C M Schonhoff; P Mitra; W Poluha; S Lambert; P J Quesenberry; N S Litofsky; L D Recht; R Nabi; S J Miller; S Ohta; B G Neel; A H Ross
Journal:  J Neurosci       Date:  2000-02-15       Impact factor: 6.167

2.  Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

Authors:  S R D'Mello; K Borodezt; S P Soltoff
Journal:  J Neurosci       Date:  1997-03-01       Impact factor: 6.167

3.  Expression of mRNA for Akt, serine-threonine protein kinase, in the brain during development and its transient enhancement following axotomy of hypoglossal nerve.

Authors:  Y Owada; A Utsunomiya; T Yoshimoto; H Kondo
Journal:  J Mol Neurosci       Date:  1997-08       Impact factor: 3.444

4.  Localization of mRNAs for novel, atypical as well as conventional protein kinase C (PKC) isoforms in the brain of developing and mature rats.

Authors:  H Minami; Y Owada; R Suzuki; Y Handa; H Kondo
Journal:  J Mol Neurosci       Date:  2000-10       Impact factor: 2.866

5.  Reciprocal interactions between prostaglandin E2- and estradiol-dependent signaling pathways in the injured zebra finch brain.

Authors:  Alyssa L Pedersen; Colin J Saldanha
Journal:  J Neuroinflammation       Date:  2017-12-29       Impact factor: 8.322

  5 in total

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