Literature DB >> 8747284

Refinements in the one-stage procedure for management of chronic osteomyelitis.

P J Guelinckx1, N K Sinsel.   

Abstract

Posttraumatic osteomyelitis remains a frequent problem and requires aggressive surgical treatment to be cured. Radical debridement of all involved soft and hard tissues, obliteration of dead space, and neovascularization of the involved area are obligatory for successful management of the disease. Microvascular free tissue transfer provides the necessary tissue bulk and neovascularization to reconstruct the resulting defect. The transplanted muscle can be optimally mobilized and adjusted in size to obliterate the dead space in contrast to local transposition flaps. This is facilitated by smoothening the bony cavity using a rotating drill system. With an optimal interface between the muscle and the wall of the cavity, small foci of infection can be eliminated. Moreover after free muscle transfer, the optimal environment for secondary bone reconstruction is created. These principles of radical debridement combined with muscle transfer for dead space obliteration, are generally accepted in literature. Nevertheless to achieve this goal several different treatment schedules of repetitive debridements, prolonged antibiotic regimes, and finally various flap transfers have been advocated. We present 16 patients with chronic osteomyelitis treated with radical debridement and immediate free muscle transfer using the latissimus dorsi muscle preferably. Postoperatively an antibiotic course of only 12 days was given. With a mean follow-up of 2 years all patients remained symptom free. Therefore, our results indicate that this long-term problem can be solved by a one-stage procedure using a free flap combined with a short course of antibiotics. However definite conclusions should be reserved for 20 years.

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Year:  1995        PMID: 8747284     DOI: 10.1002/micr.1920160906

Source DB:  PubMed          Journal:  Microsurgery        ISSN: 0738-1085            Impact factor:   2.425


  7 in total

1.  Osteomyelitis of the foot and toe in adults is a surgical disease.

Authors:  Stephen J Morewitz
Journal:  Ann Surg       Date:  2006-03       Impact factor: 12.969

2.  Cost-effectiveness of using Polyheal compared with surgery in the management of chronic wounds with exposed bones and/or tendons due to trauma in France, Germany and the UK.

Authors:  Julian F Guest; Erikas Sladkevicius; Monica Panca
Journal:  Int Wound J       Date:  2013-03-13       Impact factor: 3.315

3.  Latissimus dorsi free flap salvage of recurrent chronic osteomyelitis with simultaneous elbow interposition arthroplasty.

Authors:  Mark Henry
Journal:  Hand (N Y)       Date:  2007-07-14

4.  Treatment of deep cavities using a perforator-based island flap with partial de-epithelization.

Authors:  Jung Woo Chang; Se Won Oh; Jeongseok Oh; M Seung Suk Choi
Journal:  BMC Surg       Date:  2018-11-12       Impact factor: 2.102

5.  Insights into treatment and outcome of fracture-related infection: a systematic literature review.

Authors:  H Bezstarosti; E M M Van Lieshout; L W Voskamp; K Kortram; W Obremskey; M A McNally; W J Metsemakers; M H J Verhofstad
Journal:  Arch Orthop Trauma Surg       Date:  2018-10-20       Impact factor: 3.067

6.  Salvage of Upper Limb following a Severe Crushing Trauma: Immediate Reconstruction with a Free Flap and Subsequent Hyperbaric Oxygen Therapy.

Authors:  M P Serra; P Longhi
Journal:  Case Rep Med       Date:  2009-05-27

7.  Development of a Novel Model for the Assessment of Dead-Space Management in Soft Tissue.

Authors:  Rema A Oliver; Vedran Lovric; Yan Yu; Chris Christou; Sean S Aiken; John J Cooper; William R Walsh
Journal:  PLoS One       Date:  2015-08-25       Impact factor: 3.240

  7 in total

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