Literature DB >> 8746410

Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32.

M W Lin1, D Curtis, N Williams, M Arranz, S Nanko, D Collier, P McGuffin, R Murray, M Owen, M Gill.   

Abstract

Family, twin and adoption studies highlight the influence of genes in the aetiology of schizophrenia, though the mode of inheritance is unclear. We have been conducting a systematic search for major genes in schizophrenia using a series of multiply affected families and report preliminary results of linkage under heterogeneity with markers on chromosome 13. A lod2 score of 1.61 for marker D13S144 was obtained at theta = 0 and alpha of 0.5 and nearby markers also produced positive values.

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Year:  1995        PMID： 8746410     DOI： 10.1097/00041444-199505030-00004

Source DB:  PubMed          Journal:  Psychiatr Genet        ISSN： 0955-8829            Impact factor:   2.458


  13 in total

1.  Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23.

Authors:  H M Gurling; G Kalsi; J Brynjolfson; T Sigmundsson; R Sherrington; B S Mankoo; T Read; P Murphy; E Blaveri; A McQuillin; H Petursson; D Curtis
Journal:  Am J Hum Genet       Date:  2001-03       Impact factor: 11.025

2.  Genomewide multipoint linkage analysis of seven extended Palauan pedigrees with schizophrenia, by a Markov-chain Monte Carlo method.

Authors:  N J Camp; S L Neuhausen; J Tiobech; A Polloi; H Coon; M Myles-Worsley
Journal:  Am J Hum Genet       Date:  2001-10-19       Impact factor: 11.025

Review 3.  Molecular genetics of schizophrenia: a critical review.

Authors:  Neeraj Berry; Vaidehi Jobanputra; Hemraj Pal
Journal:  J Psychiatry Neurosci       Date:  2003-11       Impact factor: 6.186

Review 4.  Linkage studies of schizophrenia.

Authors:  Brien Riley
Journal:  Neurotox Res       Date:  2004       Impact factor: 3.911

5.  Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III.

Authors:  D F Levinson; P Holmans; R E Straub; M J Owen; D B Wildenauer; P V Gejman; A E Pulver; C Laurent; K S Kendler; D Walsh; N Norton; N M Williams; S G Schwab; B Lerer; B J Mowry; A R Sanders; S E Antonarakis; J L Blouin; J F DeLeuze; J Mallet
Journal:  Am J Hum Genet       Date:  2000-08-02       Impact factor: 11.025

6.  Linkage of familial schizophrenia to chromosome 13q32.

Authors:  L M Brzustowicz; W G Honer; E W Chow; D Little; J Hogan; K Hodgkinson; A S Bassett
Journal:  Am J Hum Genet       Date:  1999-10       Impact factor: 11.025

7.  Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.

Authors:  Ilya Chumakov; Marta Blumenfeld; Oxana Guerassimenko; Laurent Cavarec; Marta Palicio; Hadi Abderrahim; Lydie Bougueleret; Caroline Barry; Hiroaki Tanaka; Philippe La Rosa; Anne Puech; Nadia Tahri; Annick Cohen-Akenine; Sylvain Delabrosse; Sébastien Lissarrague; Françoise-Pascaline Picard; Karelle Maurice; Laurent Essioux; Philippe Millasseau; Pascale Grel; Virginie Debailleul; Anne-Marie Simon; Dominique Caterina; Isabelle Dufaure; Kattayoun Malekzadeh; Maria Belova; Jian-Jian Luan; Michel Bouillot; Jean-Luc Sambucy; Gwenael Primas; Martial Saumier; Nadia Boubkiri; Sandrine Martin-Saumier; Myriam Nasroune; Hélène Peixoto; Arnaud Delaye; Virginie Pinchot; Mariam Bastucci; Sophie Guillou; Magali Chevillon; Ricardo Sainz-Fuertes; Said Meguenni; Joan Aurich-Costa; Dorra Cherif; Anne Gimalac; Cornelia Van Duijn; Denis Gauvreau; Gail Ouellette; Isabel Fortier; John Raelson; Tatiana Sherbatich; Nadejda Riazanskaia; Evgeny Rogaev; Peter Raeymaekers; Jeroen Aerssens; Frank Konings; Walter Luyten; Fabio Macciardi; Pak C Sham; Richard E Straub; Daniel R Weinberger; Nadine Cohen; Daniel Cohen; Gail Ouelette; John Realson
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-03       Impact factor: 11.205

8.  Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans.

Authors:  Bin Xu; Abigail Woodroffe; Laura Rodriguez-Murillo; J Louw Roos; Elizabeth J van Rensburg; Gonçalo R Abecasis; Joseph A Gogos; Maria Karayiorgou
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-11       Impact factor: 11.205

9.  Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia.

Authors:  Nicholas J Bass; Susmita R Datta; Andrew McQuillin; Vinay Puri; Khalid Choudhury; Srinivasa Thirumalai; Jacob Lawrence; Digby Quested; Jonathan Pimm; David Curtis; Hugh Md Gurling
Journal:  Behav Brain Funct       Date:  2009-07-08       Impact factor: 3.759

10.  Linkage replication for chromosomal region 13q32 in schizophrenia: evidence from a Brazilian pilot study on early onset schizophrenia families.

Authors:  Ary Gadelha; Vanessa Kiyomi Ota; Jose Paya Cano; Maria Isabel Melaragno; Marilia A C Smith; Jair de Jesus Mari; Rodrigo A Bressan; Sintia Iole Belangero; Gerome Breen
Journal:  PLoS One       Date:  2012-12-31       Impact factor: 3.240
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