Literature DB >> 8744356

Ribozymes: structure and mechanism in RNA catalysis.

W G Scott1, A Klug.   

Abstract

The hammerhead RNA is a small catalytic RNA found in a number of RNA virus genomes and virus-like RNAs. The recently determined crystal structures of hammerhead ribozymes reveal how a small RNA motif can fold up into a conformation suitable for mediating RNA cleavage.

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Year:  1996        PMID： 8744356

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  20 in total

1.  Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations.

Authors:  J L O'Rear; S Wang; A L Feig; L Beigelman; O C Uhlenbeck; D Herschlag
Journal:  RNA       Date:  2001-04       Impact factor: 4.942

2.  Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA.

Authors:  T Kuwabara; M Warashina; T Tanabe; K Tani; S Asano; K Taira
Journal:  Nucleic Acids Res       Date:  1997-08-01       Impact factor: 16.971

3.  Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme.

Authors:  T Hermann; P Auffinger; W G Scott; E Westhof
Journal:  Nucleic Acids Res       Date:  1997-09-01       Impact factor: 16.971

4.  Protein-RNA interactions: a structural analysis.

Authors:  S Jones; D T Daley; N M Luscombe; H M Berman; J M Thornton
Journal:  Nucleic Acids Res       Date:  2001-02-15       Impact factor: 16.971

5.  Evolutionary origin of a plant mitochondrial group II intron from a reverse transcriptase/maturase-encoding ancestor.

Authors:  Daniela Ahlert; Katrin Piepenburg; Jörg Kudla; Ralph Bock
Journal:  J Plant Res       Date:  2006-06-09       Impact factor: 2.629

6.  Targeted cleavage: tuneable cis-cleaving ribozymes.

Authors:  John J Rossi
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-12       Impact factor: 11.205

7.  Generation of circular RNAs and trans-cleaving catalytic RNAs by rolling transcription of circular DNA oligonucleotides encoding hairpin ribozymes.

Authors:  A M Diegelman; E T Kool
Journal:  Nucleic Acids Res       Date:  1998-07-01       Impact factor: 16.971

8.  In vitro selection of hammerhead ribozymes containing a bulged nucleotide in stem II.

Authors:  J B Thomson; S T Sigurdsson; A Zeuch; F Eckstein
Journal:  Nucleic Acids Res       Date:  1996-11-15       Impact factor: 16.971

9.  Catalytic cleavage of cis- and trans-acting antigenomic delta ribozymes in the presence of various divalent metal ions.

Authors:  J Wrzesinski; M Legiewicz; B Smólska; J Ciesiolka
Journal:  Nucleic Acids Res       Date:  2001-11-01       Impact factor: 16.971

Review 10.  Unveiling Human Non-Random Genome Editing Mechanisms Activated in Response to Chronic Environmental Changes: I. Where Might These Mechanisms Come from and What Might They Have Led To?

Authors:  Loris Zamai
Journal:  Cells       Date:  2020-10-27       Impact factor: 6.600
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