Literature DB >> 8744009

Regional myocardial oxygen tension: 19F MRI of sequestered perfluorocarbon.

H P Shukla1, R P Mason, N Bansal, P P Antich.   

Abstract

A novel noninvasive method of measuring local myocardial oxygen tension (pO2) in the perfused rat heart using 19F MRI is demonstrated. Tissue pO2 was determined on the basis of the 19F spin-lattice relaxation rate (R1) of perflubron (perfluorooctyl bromide) sequestered in the heart after IV infusion of an emulsion. Spectroscopic measurement of R1 was previously used to measure a global weighted average of oxygen status. 19F MRI now provides 3D spatial resolution indicating local cardiac pO2 under normally perfused, globally ischemic, and regionally ischemic conditions.

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Year:  1996        PMID： 8744009     DOI： 10.1002/mrm.1910350607

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  11 in total

Review 1.  Perfluorocarbon nanoparticles for physiological and molecular imaging and therapy.

Authors:  Junjie Chen; Hua Pan; Gregory M Lanza; Samuel A Wickline
Journal:  Adv Chronic Kidney Dis       Date:  2013-11       Impact factor: 3.620

2.  Oxygen Sensing with Perfluorocarbon-Loaded Ultraporous Mesostructured Silica Nanoparticles.

Authors:  Amani L Lee; Clifford T Gee; Bradley P Weegman; Samuel A Einstein; Adam R Juelfs; Hattie L Ring; Katie R Hurley; Sam M Egger; Garrett Swindlehurst; Michael Garwood; William C K Pomerantz; Christy L Haynes
Journal:  ACS Nano       Date:  2017-05-22       Impact factor: 15.881

Review 3.  New frontiers and developing applications in 19F NMR.

Authors:  Jian-Xin Yu; Rami R Hallac; Srinivas Chiguru; Ralph P Mason
Journal:  Prog Nucl Magn Reson Spectrosc       Date:  2012-11-02       Impact factor: 9.795

4.  An oxygen-consuming phantom simulating perfused tissue to explore oxygen dynamics and (19)F MRI oximetry.

Authors:  Steven H Ubert Baete; Jan Vandecasteele; Luc Colman; Wilfried De Neve; Yves De Deene
Journal:  MAGMA       Date:  2010-06-25       Impact factor: 2.310

5.  Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with 19F MRI in a Murine Model.

Authors:  Fanny Chapelin; Benjamin I Leach; Ruifeng Chen; Deanne Lister; Karen Messer; Hideho Okada; Eric T Ahrens
Journal:  Radiol Imaging Cancer       Date:  2021-01-22

6.  Visualization of immune cell infiltration in experimental viral myocarditis by (19)F MRI in vivo.

Authors:  Christoph Jacoby; Nadine Borg; Philipp Heusch; Martina Sauter; Florian Bönner; Reinhard Kandolf; Karin Klingel; Jürgen Schrader; Ulrich Flögel
Journal:  MAGMA       Date:  2013-07-04       Impact factor: 2.310

7.  Non-invasive imaging of oxygen concentration in a complex in vitro biofilm infection model using 19 F MRI: Persistence of an oxygen sink despite prolonged antibiotic therapy.

Authors:  Jeffrey W Simkins; Philip S Stewart; Sarah L Codd; Joseph D Seymour
Journal:  Magn Reson Med       Date:  2019-08-02       Impact factor: 4.668

Review 8.  Liquid perfluorocarbons as contrast agents for ultrasonography and (19)F-MRI.

Authors:  Raquel Díaz-López; Nicolas Tsapis; Elias Fattal
Journal:  Pharm Res       Date:  2009-11-10       Impact factor: 4.200

Review 9.  Fluorine-containing nanoemulsions for MRI cell tracking.

Authors:  Jelena M Janjic; Eric T Ahrens
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2009 Sep-Oct

10.  Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence.

Authors:  Lingzhi Hu; Junjie Chen; Xiaoxia Yang; Shelton D Caruthers; Gregory M Lanza; Samuel A Wickline
Journal:  Magn Reson Med       Date:  2012-08-22       Impact factor: 4.668
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