Literature DB >> 8743896

Apolipoprotein E as a risk factor for coronary heart disease: a genetic and molecular biology approach.

P de Knijff1, L M Havekes.   

Abstract

For a long time it has been suggested that apolipoprotein E4 is a major risk factor for coronary heart disease although indisputable proof has been lacking. However, context-dependent influences of apolipoprotein E polymorphism on the risk for coronary heart disease have been reported; that is, depending on ethnic origin, gender and lifestyle, apolipoprotein E4 confers a major risk factor for coronary heart disease.

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Year:  1996        PMID: 8743896     DOI: 10.1097/00041433-199604000-00002

Source DB:  PubMed          Journal:  Curr Opin Lipidol        ISSN: 0957-9672            Impact factor:   4.776


  3 in total

1.  Apolipoprotein E gene polymorphisms and serum cholesterol in healthy Irish adults: a proposed genetic marker for coronary artery disease risk.

Authors:  D Sheehan; T Bennett; K Cashman
Journal:  Ir J Med Sci       Date:  2000 Jan-Mar       Impact factor: 1.568

Review 2.  Dissection of the complex role of apolipoprotein E in lipoprotein metabolism and atherosclerosis using mouse models.

Authors:  K W van Dijk; M H Hofker; L M Havekes
Journal:  Curr Atheroscler Rep       Date:  1999-09       Impact factor: 5.113

3.  Genetic polymorphisms in LDLR, APOB, PCSK9 and other lipid related genes associated with familial hypercholesterolemia in Malaysia.

Authors:  Say-Hean Lye; Jagdish Kaur Chahil; Pramod Bagali; Livy Alex; Jamunarani Vadivelu; Wan Azman Wan Ahmad; Siew-Pheng Chan; Meow-Keong Thong; Shamsul Mohd Zain; Rosmawati Mohamed
Journal:  PLoS One       Date:  2013-04-08       Impact factor: 3.240

  3 in total

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