Literature DB >> 8742783

Dual inhibitors of enkephalin-degrading enzymes (neutral endopeptidase 24.11 and aminopeptidase N) as potential new medications in the management of pain and opioid addiction.

B P Roques1, F Noble.   

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Year:  1995        PMID: 8742783

Source DB:  PubMed          Journal:  NIDA Res Monogr        ISSN: 1046-9516


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  12 in total

1.  Exploring the Backbone of Enkephalins To Adjust Their Pharmacological Profile for the δ-Opioid Receptor.

Authors:  Arnaud Proteau-Gagné; Véronique Bournival; Kristina Rochon; Yves L Dory; Louis Gendron
Journal:  ACS Chem Neurosci       Date:  2010-09-17       Impact factor: 4.418

2.  Preparation and evaluation at the delta opioid receptor of a series of linear leu-enkephalin analogues obtained by systematic replacement of the amides.

Authors:  Kristina Rochon; Arnaud Proteau-Gagné; Philippe Bourassa; Jean-François Nadon; Jérome Côté; Véronique Bournival; Fernand Gobeil; Brigitte Guérin; Yves L Dory; Louis Gendron
Journal:  ACS Chem Neurosci       Date:  2013-05-20       Impact factor: 4.418

Review 3.  Novel neuropeptides as ligands of orphan G protein-coupled receptors.

Authors:  Yan Zhang; Zhiwei Wang; Gregory Scott Parks; Olivier Civelli
Journal:  Curr Pharm Des       Date:  2011       Impact factor: 3.116

4.  Similar decrease in spontaneous morphine abstinence by methadone and RB 101, an inhibitor of enkephalin catabolism.

Authors:  F Ruiz; M C Fournié-Zaluski; B P Roques; R Maldonado
Journal:  Br J Pharmacol       Date:  1996-09       Impact factor: 8.739

5.  Synthesis and Opioid Activity of Tyr1 -ψ[(Z)CF=CH]-Gly2 and Tyr1 -ψ[(S)/(R)-CF3 CH-NH]-Gly2 Leu-enkephalin Fluorinated Peptidomimetics.

Authors:  Somnath Narayan Karad; Mohan Pal; Rachel S Crowley; Thomas E Prisinzano; Ryan A Altman
Journal:  ChemMedChem       Date:  2017-04-05       Impact factor: 3.466

6.  Blockade of morphine-induced behavioral sensitization by a combination of amisulpride and RB101, comparison with classical opioid maintenance treatments.

Authors:  L Cordonnier; M Sanchez; B P Roques; F Noble
Journal:  Br J Pharmacol       Date:  2007-03-12       Impact factor: 8.739

Review 7.  Association of enkephalin catabolism inhibitors and CCK-B antagonists: a potential use in the management of pain and opioid addiction.

Authors:  B P Roques; F Noble
Journal:  Neurochem Res       Date:  1996-11       Impact factor: 3.996

8.  Synthesis of Leu-Enkephalin Peptidomimetics Containing Trifluoromethylalkenes as Amide Isopolar Mimics.

Authors:  Venkateswararao Eeda; Manikandan Selvaraju; Ryan A Altman
Journal:  J Fluor Chem       Date:  2018-12-11       Impact factor: 2.050

9.  Tyr1-ψ[( Z)CF═CH]-Gly2 Fluorinated Peptidomimetic Improves Distribution and Metabolism Properties of Leu-Enkephalin.

Authors:  Ryan A Altman; Krishna K Sharma; Lian G Rajewski; Paul C Toren; Michael J Baltezor; Mohan Pal; Somnath N Karad
Journal:  ACS Chem Neurosci       Date:  2018-04-19       Impact factor: 4.418

10.  The Analgesic Activity of Bestatin as a Potent APN Inhibitor.

Authors:  Mei-Rong Jia; Tao Wei; Wen-Fang Xu
Journal:  Front Neurosci       Date:  2010-06-28       Impact factor: 4.677

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