Literature DB >> 8742515

The effect of 2-chloroadenosine on the ATP level Na,K ATPase activity in experimental brain ischemia of gerbil.

N Türközkan1, S Aykol, A Bilgihan, O Yavuz, B Cayci, F Doğulu.   

Abstract

T1. The effect of 2-chloroadenosine, an adenosine analogue, on brain ATP level and Na,K ATPase activity in ischemia and reperfusion was studied. 2. Na,K ATPase activity decreased in both ischemia and reperfusion. Although the ATP level decreased in ischemia, it increased with reperfusion (P < 0.05). 3. It is concluded that 2-chloroadenosine treatment influenced ATP production and Na,K ATPase activity in ischemia and reperfusion (P < 0.05).

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Year:  1996        PMID: 8742515     DOI: 10.1016/0306-3623(95)00084-4

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN: 0306-3623


  1 in total

1.  Preconditioning prevents the inhibition of Na+,K+-ATPase activity after brain ischemia.

Authors:  A T de Souza Wyse; E L Streck; P Worm; A Wajner; F Ritter; C A Netto
Journal:  Neurochem Res       Date:  2000-07       Impact factor: 3.996

  1 in total

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