| Literature DB >> 8742025 |
K Ui-Tei1, S Sato, T Miyake, Y Miyata.
Abstract
Apoptotic type cell death was induced by the calcium ionophore, A23187, in a Drosophila CNS derived cell line, ML-DmBG2-c2. It was judged by the ultrastructural observations and internucleosomal DNA fragmentation, typical characteristics of apoptosis. The ionophore failed to induce apoptosis in Ca2+- free medium, which suggests that the increase of intracellular Ca2+ concentration by the treatment of A23187 triggers apoptosis in the clonal cells.Entities:
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Year: 1996 PMID： 8742025 DOI： 10.1016/0304-3940(95)12292-3
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046