Literature DB >> 8740649

Strategies for cancer gene therapy using adenoviral vectors.

V Descamps1, M T Duffour, M C Mathieu, N Fernandez, L Cordier, M A Abina, E Kremer, M Perricaudet, H Haddada.   

Abstract

Modification of tumor cells using gene transfer either to enhance host immunity or to act directly on tumor cells is being intensively studied in animal models. Remarkable results have yielded to approved clinical protocols in the treatment of cancer patients using this approach. Several methods of gene delivery have been developed. This article is particularly devoted to the interest of the use of adenoviral vectors in the different strategies of cancer gene therapy.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8740649     DOI： 10.1007/bf00204748

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  67 in total

Review 1.  The origin and function of tumor-associated macrophages.

Authors:  A Mantovani; B Bottazzi; F Colotta; S Sozzani; L Ruco
Journal:  Immunol Today       Date:  1992-07

2.  Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression.

Authors:  W E Mercer; M T Shields; D Lin; E Appella; S J Ullrich
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-01       Impact factor: 11.205

3.  Stable expression of the wild-type p53 gene in human lung cancer cells after retrovirus-mediated gene transfer.

Authors:  D W Cai; T Mukhopadhyay; Y Liu; T Fujiwara; J A Roth
Journal:  Hum Gene Ther       Date:  1993-10       Impact factor: 5.695

4.  A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.

Authors:  P van der Bruggen; C Traversari; P Chomez; C Lurquin; E De Plaen; B Van den Eynde; A Knuth; T Boon
Journal:  Science       Date:  1991-12-13       Impact factor: 47.728

Review 5.  Antitumor effects of interleukin-12 (IL-12): applications for the immunotherapy and gene therapy of cancer.

Authors:  H Tahara; M T Lotze
Journal:  Gene Ther       Date:  1995-03       Impact factor: 5.250

6.  The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

Authors:  S M Freeman; C N Abboud; K A Whartenby; C H Packman; D S Koeplin; F L Moolten; G N Abraham
Journal:  Cancer Res       Date:  1993-11-01       Impact factor: 12.701

7.  Abrogation of metastatic properties of tumour cells by de novo expression of H-2K antigens following H-2 gene transfection.

Authors:  R Wallich; N Bulbuc; G J Hämmerling; S Katzav; S Segal; M Feldman
Journal:  Nature       Date:  1985 May 23-29       Impact factor: 49.962

8.  High-efficiency gene transfer and high-level expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus.

Authors:  W W Zhang; X Fang; W Mazur; B A French; R N Georges; J A Roth
Journal:  Cancer Gene Ther       Date:  1994-03       Impact factor: 5.987

9.  Interleukin 7 induces CD4+ T cell-dependent tumor rejection.

Authors:  H Hock; M Dorsch; T Diamantstein; T Blankenstein
Journal:  J Exp Med       Date:  1991-12-01       Impact factor: 14.307

10.  Antitumor activity of recombinant interleukin 6 in mice.

Authors:  J J Mulé; J K McIntosh; D M Jablons; S A Rosenberg
Journal:  J Exp Med       Date:  1990-03-01       Impact factor: 14.307
View more
  1 in total

1.  Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers.

Authors:  K Jooss; Y Yang; K J Fisher; J M Wilson
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.