Literature DB >> 8739340

Morphometric analysis of fetal rat lung after the administration of Pyralene-3000.

M Vrecl1, A Pogacnik, J Lorger, S V Bavdek.   

Abstract

The effects of the application of commercial low chlorinated PCB Pyralene-3000 on rat lung development during late gestation were studied. In the developing lungs (17.5 to 21.5 days) the volume density (Vv) of a particular compartment and length density of potential air spaces (Lv) were determined. Significant difference (p < 0.01) in epithelium to mesenchyme ratio (Epi/Mes) occurred between the control and treated groups on day 20.5 due to an increased volume proportion of mesenchyme (Vvmes) in the treated group suggesting a small delay in maturation. Decreased volume proportion of potential airspaces (Vvair) was observed on days 18.5 and 20.5. However, no differences were found on day 21.5 in any variables studied.

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Year:  1996        PMID： 8739340     DOI： 10.1007/bf02346344

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  6 in total

1.  The interference of polychlorinated biphenyls (Aroclor 1254) with membrane regulation of the activities of cytochromes P-450C21 and P-450(17) alpha,lyase in guinea-pig adrenal microsomes.

Authors:  D Goldman; A Yawetz
Journal:  J Steroid Biochem Mol Biol       Date:  1992-03       Impact factor: 4.292

Review 2.  Cellular timing of fetal lung development.

Authors:  J Torday
Journal:  Semin Perinatol       Date:  1992-04       Impact factor: 3.300

3.  Immunochemical localization of Clara cell protein by light and electron microscopy in conducting airways of fetal and neonatal hamster lung.

Authors:  J M Strum; G Singh; S L Katyal; E M McDowell
Journal:  Anat Rec       Date:  1990-05

4.  Sex differences in development of fetal rat lung. II. Quantitative morphology of epithelial-mesenchymal interactions.

Authors:  I Y Adamson; G M King
Journal:  Lab Invest       Date:  1984-04       Impact factor: 5.662

5.  Partial purification of a binding protein for polychlorinated biphenyls from rat lung cytosol: physicochemical and immunochemical characterization.

Authors:  J Lund; L Nordlund; J A Gustafsson
Journal:  Biochemistry       Date:  1988-10-04       Impact factor: 3.162

6.  Potent inhibition of both human interferon-gamma production and biologic activity by the Clara cell protein CC16.

Authors:  I Dierynck; A Bernard; H Roels; M De Ley
Journal:  Am J Respir Cell Mol Biol       Date:  1995-02       Impact factor: 6.914
  6 in total

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