Literature DB >> 8738618

The effects of thiotepa, mitomycin C, BCG and interferon instillation on urothelium.

O Polat1, C Gündoğdu, A Demirel, Y Bayraktar, O Gül, M Ozbilge.   

Abstract

The effects of Thiotepa, Mitomycin C, BCG and Interferon on urothelium were researched in rabbits. Early changes of a contracted bladder such as fibroblastic atypia and sub-epithelial plaque were seen in all groups in different rates. This rate in the Thiotepa and BCG groups was 100% and in the Mitomycin C and Interferon groups 60%. There was no urothelial dysplasia in the BCG and Interferon groups, whereas in the Thiotepa group 100% and in the Mitomycin C group 40% were seen. In conclusion, urothelial dysplasia or fibroblastic atypia in random biopsies were criteria to prevent further complications in intravesical therapies.

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Year:  1996        PMID： 8738618     DOI： 10.1007/bf02550136

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  9 in total

1.  Cancer statistics, 1990.

Authors:  E Silverberg; C C Boring; T S Squires
Journal:  CA Cancer J Clin       Date:  1990 Jan-Feb       Impact factor: 508.702

2.  Secondary hematologic neoplasm after intravesical chemotherapy for superficial bladder carcinoma.

Authors:  P Sonneveld; K H Kurth; A Hagemeyer; J Abels
Journal:  Cancer       Date:  1990-01-01       Impact factor: 6.860

3.  Natural history and treatment of low and high risk superficial bladder tumors.

Authors:  H Rübben; W Lutzeyer; N Fischer; F Deutz; W Lagrange; G Giani
Journal:  J Urol       Date:  1988-02       Impact factor: 7.450

4.  Summary of workshop on carcinoma in situ of the bladder.

Authors:  G H Friedell; M S Soloway; A G Hilgar; G M Farrow
Journal:  J Urol       Date:  1986-11       Impact factor: 7.450

5.  Morphologic effects of thio-TEPA on mouse urothelium.

Authors:  W M Murphy; M S Soloway; C J Lin
Journal:  Acta Cytol       Date:  1977 Sep-Oct       Impact factor: 2.319

6.  The effect of mitomycin C on superficial bladder cancer.

Authors:  M S Soloway; W M Murphy; M D DeFuria; S Crooke; P Finebaum
Journal:  J Urol       Date:  1981-05       Impact factor: 7.450

7.  Morphologic effects of thio-TEPA on mammalian urothelium. Changes in abnormal cells.

Authors:  W M Murphy; M S Soloway; C J Lin
Journal:  Acta Cytol       Date:  1978 Nov-Dec       Impact factor: 2.319

8.  Severely contracted bladder following intravesical mitomycin C therapy.

Authors:  Z Wajsman; W McGill; L Englander; R P Huben; J E Pontes
Journal:  J Urol       Date:  1983-08       Impact factor: 7.450

9.  Intravesical therapy of low stage bladder carcinoma with mitomycin C: comparison of results in untreated and previously treated patients.

Authors:  G R Prout; P P Griffin; B N Nocks; M D DeFuria; J J Daly
Journal:  J Urol       Date:  1982-06       Impact factor: 7.450
  9 in total
  1 in total

1.  The effect of thermochemotherapy with mitomycin C on normal bladder urothelium, an experimental study.

Authors:  Murat Uçar; Muammer Altok; Mehmet Umul; Dilek Bayram; İlkay Armağan; Mustafa Güneş; Tahsin Çapkin; Sedat Soyupek
Journal:  Int Urol Nephrol       Date:  2016-01       Impact factor: 2.370
  1 in total

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