| Literature DB >> 8737947 |
Abstract
An HPLC method using a reverse phase system, an isocratic mobile phase and 1-phenyl-1,2 ethanediol as internal standard and a well diffusion bioassay using a strain of Candida pseudotropicalis were compared for the measurement of fluconazole in serum. Both methods permit determination of fluconazole in the range from 1 mg/L to 30 mg/L. The correlation between both methods was found to be r = 0.89. Both methods are useful for monitoring the serum level of fluconazole in clinical routine work.Entities:
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Year: 1996 PMID： 8737947 DOI： 10.1016/s0934-8840(96)80126-5
Source DB: PubMed Journal: Zentralbl Bakteriol ISSN： 0934-8840