Literature DB >> 8737149

The effect of rifampicin on adaptive resistance of Pseudomonas aeruginosa to aminoglycosides.

Y Q Xiong1, J Caillon, H Drugeon, G Potel, D Baron.   

Abstract

Using the dynamic chequerboard technique, we confirmed that rifampicin produces a synergistic bactericidal effect when combined with amikacin or netilmicin. Adaptive resistance was suppressed when rifampicin was added to aminoglycoside after, but not during, first exposure to amikacin or netilmicin. The effect of rifampicin on adaptive resistance could account for the synergy between rifampicin and aminoglycosides.

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Year:  1996        PMID： 8737149     DOI： 10.1093/jac/37.5.993

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  4 in total

Review 1.  Aminoglycoside adaptive resistance: importance for effective dosage regimens.

Authors:  M L Barclay; E J Begg
Journal:  Drugs       Date:  2001       Impact factor: 9.546

2.  Adaptive resistance of Pseudomonas aeruginosa induced by aminoglycosides and killing kinetics in a rabbit endocarditis model.

Authors:  Y Q Xiong; J Caillon; M F Kergueris; H Drugeon; D Baron; G Potel; A S Bayer
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191

3.  Potentiation of Aminoglycoside Activity in Pseudomonas aeruginosa by Targeting the AmgRS Envelope Stress-Responsive Two-Component System.

Authors:  Keith Poole; Christie Gilmour; Maya A Farha; Erin Mullen; Calvin Ho-Fung Lau; Eric D Brown
Journal:  Antimicrob Agents Chemother       Date:  2016-05-23       Impact factor: 5.191

4.  MexXY-OprM efflux pump is necessary for a adaptive resistance of Pseudomonas aeruginosa to aminoglycosides.

Authors:  Didier Hocquet; Christelle Vogne; Farid El Garch; Anne Vejux; Naomasa Gotoh; Angela Lee; Olga Lomovskaya; Patrick Plésiat
Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191
  4 in total

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