| Literature DB >> 8735844 |
D H Boschelli1, D T Connor, M E Lesch, D J Schrier.
Abstract
The surface levels of ICAM-1 and E-selectin on activated endothelial cells can be reduced by 3-alkoxybenzo[b]thiophene-2-carboxamides. This property is shared by several N-alkylthiopyridine substituted imides. Combining structural elements of these two diverse series lead to a new class of small molecule inhibitors of adhesion molecule expression.Entities:
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Year: 1996 PMID： 8735844 DOI： 10.1016/0968-0896(96)00046-6
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641