Literature DB >> 8733435

A unifying hypothesis for the mechanism of NSAID related gastrointestinal toxicity.

T Mahmud1, D L Scott, I Bjarnason.   

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Year:  1996        PMID: 8733435      PMCID: PMC1010136          DOI: 10.1136/ard.55.4.211

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


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  25 in total

1.  BIOCHEMICAL PROPERTIES OF ANTI-INFLAMMATORY DRUGS--III. UNCOUPLING OF OXIDATIVE PHOSPHORYLATION IN A CONNECTIVE TISSUE (CARTILAGE) AND LIVER MITOCHONDRIA BY SALICYLATE ANALOGUES: RELATIONSHIP OF STRUCTURE TO ACTIVITY.

Authors:  M W WHITEHOUSE
Journal:  Biochem Pharmacol       Date:  1964-03       Impact factor: 5.858

2.  Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

Authors:  J R Vane
Journal:  Nat New Biol       Date:  1971-06-23

3.  Effect of acetylsalicylic acid on gastric mucosa. II. Mucosal ATP and phosphocreatine content, and salicylate effects on mitochondrial metabolism.

Authors:  J G Spenney; M Bhown
Journal:  Gastroenterology       Date:  1977-11       Impact factor: 22.682

Review 4.  Inflammation and the mechanism of action of anti-inflammatory drugs.

Authors:  J Vane; R Botting
Journal:  FASEB J       Date:  1987-08       Impact factor: 5.191

5.  Aspirin-induced ultrastructural changes in human gastric mucosa: correlation with potential difference.

Authors:  W N Baskin; K J Ivey; W J Krause; G E Jeffrey; R T Gemmell
Journal:  Ann Intern Med       Date:  1976-09       Impact factor: 25.391

6.  Effects of nonsteroidal, antiinflammatory drugs on gastrointestinal injury and prostanoid generation in healthy volunteers.

Authors:  R A Levine; S Petokas; J Nandi; D Enthoven
Journal:  Dig Dis Sci       Date:  1988-06       Impact factor: 3.199

7.  Occluding junctions and cytoskeletal components in a cultured transporting epithelium.

Authors:  I Meza; G Ibarra; M Sabanero; A Martínez-Palomo; M Cereijido
Journal:  J Cell Biol       Date:  1980-12       Impact factor: 10.539

8.  Role of bacteria in gastric ulceration produced by indomethacin in the rat: cytoprotective action of antibiotics.

Authors:  H Satoh; P H Guth; M I Grossman
Journal:  Gastroenterology       Date:  1983-03       Impact factor: 22.682

9.  Effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine.

Authors:  I Bjarnason; P Williams; P Smethurst; T J Peters; A J Levi
Journal:  Gut       Date:  1986-11       Impact factor: 23.059

10.  Aspirin can inhibit gastric mucosal cyclo-oxygenase without causing lesions in rat.

Authors:  M Ligumsky; E M Golanska; D G Hansen; G L Kauffman
Journal:  Gastroenterology       Date:  1983-04       Impact factor: 22.682

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  18 in total

1.  Anti-inflammatory drugs and variceal bleeding: a case-control study.

Authors:  V De Lédinghen; D Heresbach; O Fourdan; P Bernard; M P Liebaert-Bories; J B Nousbaum; A Gourlaouen; M C Becker; D Ribard; P Ingrand; C Silvain; M Beauchant
Journal:  Gut       Date:  1999-02       Impact factor: 23.059

2.  Evidence-based medicine or medicines-based evidence?

Authors:  P Dieppe
Journal:  Ann Rheum Dis       Date:  1998-07       Impact factor: 19.103

Review 3.  Cyclo-oxygenase isoenzymes. How recent findings affect thinking about nonsteroidal anti-inflammatory drugs.

Authors:  J Y Jouzeau; B Terlain; A Abid; E Nédélec; P Netter
Journal:  Drugs       Date:  1997-04       Impact factor: 9.546

4.  Increased risk of microscopic colitis with use of proton pump inhibitors and non-steroidal anti-inflammatory drugs.

Authors:  Gwen M C Masclee; Preciosa M Coloma; Ernst J Kuipers; Miriam C J M Sturkenboom
Journal:  Am J Gastroenterol       Date:  2015-04-28       Impact factor: 10.864

Review 5.  Gastrointestinal effects of aspirin.

Authors:  Carlos Sostres; Angel Lanas
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2011-06-07       Impact factor: 46.802

Review 6.  Cyclooxygenase 2-implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives.

Authors:  F Halter; A S Tarnawski; A Schmassmann; B M Peskar
Journal:  Gut       Date:  2001-09       Impact factor: 23.059

Review 7.  Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategies.

Authors:  Urs A Boelsterli; Matthew R Redinbo; Kyle S Saitta
Journal:  Toxicol Sci       Date:  2012-10-22       Impact factor: 4.849

Review 8.  Capsule endoscopic diagnosis of nonsteroidal antiinflammatory drug-induced enteropathy.

Authors:  Laurence Maiden
Journal:  J Gastroenterol       Date:  2009-01-16       Impact factor: 7.527

9.  Enantiomers of flurbiprofen can distinguish key pathophysiological steps of NSAID enteropathy in the rat.

Authors:  T Mahmud; S Somasundaram; G Sigthorsson; R J Simpson; S Rafi; R Foster; I A Tavares; A Roseth; A J Hutt; M Jacob; J Pacy; D L Scott; J M Wrigglesworth; I Bjarnason
Journal:  Gut       Date:  1998-12       Impact factor: 23.059

10.  Clinical outcomes of various continued antiplatelet therapies in patients who were administered DAPT following the implantation of drug-eluting stents and developed gastrointestinal hemorrhage.

Authors:  Yujie Guo; Jinru Wei
Journal:  Exp Ther Med       Date:  2016-05-23       Impact factor: 2.447

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