Literature DB >> 8732171

Clinical relevance of hepatitis C virus quasispecies.

N Enomoto1, C Sato.   

Abstract

It has been shown that hepatitis C virus (HCV) populations in infected individuals are composed of quasispecies with diverse mutations. The analysis of these variants may reveal mechanisms of the persistence of HCV infection, carcinogenesis and resistance to antiviral therapy. Recently, genetic features of interferon-resistant HCV have been elucidated through the analysis of interferon-resistant quasispecies, making it possible to predict interferon efficacy by detecting interferon-resistant strains.

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Year:  1995        PMID： 8732171     DOI： 10.1111/j.1365-2893.1995.tb00040.x

Source DB:  PubMed          Journal:  J Viral Hepat        ISSN： 1352-0504            Impact factor:   3.728


  3 in total

1.  The use of SSCP analysis [corrected] to evidence genetic variability in the gene coding for immunodominant protein e2 of the BVDV.

Authors:  S Ciulli; E Galletti; F De Giorgi; M Battilani; S Prosperi
Journal:  Vet Res Commun       Date:  2008-09       Impact factor: 2.459

2.  Activation and evasion of the antiviral 2'-5' oligoadenylate synthetase/ribonuclease L pathway by hepatitis C virus mRNA.

Authors:  Jian-Qiu Han; David J Barton
Journal:  RNA       Date:  2002-04       Impact factor: 4.942

3.  Analyzing the Effects of Pretreatment Diversity on HCV Drug Treatment Responsiveness Using Bayesian Partition methods.

Authors:  Yao Fu; Gang Chen; Xuan Guo; Jing Zhang; Yi Pan
Journal:  J Bioinform Proteom Rev       Date:  2015-05-12
  3 in total

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