| Literature DB >> 8731959 |
M Li1, J Yang, Y N Hu, X T Ye, W X Ye.
Abstract
The role of AC-cAMP-PKA signal system in T cell activation was investigated by lymphocyte proliferation stimulated by anti-CD3 McAb. The results indicated that AC, cAMP and PKA play important roles in determining the responses of lymphocytes to the stimulation. Activation of AC and increase of intracellular cAMP could obviously decrease lymphocyte proliferation, and lymphocyte DNA synthesis was increased to some extent by the pretreatment of PKI.Entities:
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Year: 1995 PMID： 8731959 DOI： 10.1007/BF02887908
Source DB: PubMed Journal: J Tongji Med Univ ISSN： 0257-716X