Literature DB >> 8731947

Study on in vivo release of levonorgestrel-containing silicon capsule.

C J Wu1, X R Wu, W J Xia, R L Li.   

Abstract

The in vivo release rate of levonorgestrel-containing silicon capsule (in vitro releasing rate: 6 micrograms/d) placed in rabbits was determined. The results showed that the average release per year was 8.32 micrograms with r being 0.96000. The release pattern of the levonorgestrel-containing silicon capsule system was proved to be zero-order release. Our study provided some experimental data for clinical use of the system for birth control.

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Year:  1995        PMID： 8731947     DOI： 10.1007/BF02888228

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN： 0257-716X


  5 in total

1.  In vitro-in vivo correlation on the subcutaneous release of progestins from silicone capsules.

Authors:  Y W Chien
Journal:  Chem Pharm Bull (Tokyo)       Date:  1976-07       Impact factor: 1.645

2.  Five years' experience with levonorgestrel-releasing IUDs.

Authors:  T Luukkainen; H Allonen; M Haukkamaa; P Lähteenmäki; C G Nilsson; J Toivonen
Journal:  Contraception       Date:  1986-02       Impact factor: 3.375

3.  Effective contraception with the levonorgestrel-releasing intrauterine device: 12-month report of a European multicenter study.

Authors:  T Luukkainen; H Allonen; M Haukkamaa; P Holma; T Pyörälä; J Terho; J Toivonen; I Batar; L Lampe; K Andersson
Journal:  Contraception       Date:  1987-08       Impact factor: 3.375

4.  Ovarian function in amenorrheic and menstruating users of a levonorgestrel-releasing intrauterine device.

Authors:  C G Nilsson; P L Lähteenmäki; T Luukkainen
Journal:  Fertil Steril       Date:  1984-01       Impact factor: 7.329

5.  Two years of intrauterine contraception with levonorgestrel and with copper: a randomized comparison of the TCu 380Ag and levonorgestrel 20 mcg/day devices.

Authors:  I Sivin; J Stern; J Diaz; M M Diaz; A Faundes; S el Mahgoub; S Diaz; M Pavez; E Coutinho; C E Mattos
Journal:  Contraception       Date:  1987-03       Impact factor: 3.375
  5 in total
  2 in total

1.  Disseminated injection of vincristine-loaded silk gel improves the suppression of neuroblastoma tumor growth.

Authors:  Jasmine Zeki; Jordan S Taylor; Burcin Yavuz; Jeannine Coburn; Naohiko Ikegaki; David L Kaplan; Bill Chiu
Journal:  Surgery       Date:  2018-07-27       Impact factor: 3.982

2.  Manipulation of variables in local controlled release vincristine treatment in neuroblastoma.

Authors:  Jeannine M Coburn; Jamie Harris; Rachel Cunningham; Jasmine Zeki; David L Kaplan; Bill Chiu
Journal:  J Pediatr Surg       Date:  2017-09-04       Impact factor: 2.545
  2 in total

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