Literature DB >> 8730938

Patients with schizophrenia remember that an event has occurred, but not when.

L Rizzo1, J M Danion, M van der Linden, D Grangé.   

Abstract

BACKGROUND: The context memory deficit hypothesis of schizophrenia postulates that the long-term deficit associated with this disorder is related to a memory impairment for contextual information.
METHOD: To test this hypothesis, memory for temporal context was assessed in 33 patients with schizophrenia and 33 normal subjects, using a recency discrimination task.
RESULTS: Whereas patients were able to recall and recognise target items, they were unable to recognise from among the target items those which had been most recently learned.
CONCLUSIONS: Schizophrenia is associated with a temporal context memory deficit.

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Year:  1996        PMID: 8730938     DOI: 10.1192/bjp.168.4.427

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  11 in total

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3.  Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia.

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Journal:  Neuropsychol Rev       Date:  2003-06       Impact factor: 7.444

5.  Distinguishing familiarity-based from source-based memory performance in patients with schizophrenia.

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6.  PKBγ/AKT3 loss-of-function causes learning and memory deficits and deregulation of AKT/mTORC2 signaling: Relevance for schizophrenia.

Authors:  Kristy R Howell; Kirsten Floyd; Amanda J Law
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7.  Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D3 Receptor Blockade.

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8.  Temporal processing of past and future autobiographical events in patients with schizophrenia.

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Review 10.  Schizophrenia: What's Arc Got to Do with It?

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Journal:  Front Behav Neurosci       Date:  2017-09-20       Impact factor: 3.558

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