Literature DB >> 8730669

An investigation of light transport through scattering bodies with non-scattering regions.

M Firbank1, S R Arridge, M Schweiger, D T Delpy.   

Abstract

Near-infra-red (NIR) spectroscopy is increasingly being used for monitoring cerebral oxygenation and haemodynamics. One current concern is the effect of the clear cerebrospinal fluid upon the distribution of light in the head. There are difficulties in modelling clear layers in scattering systems. The Monte Carlo model should handle clear regions accurately, but is too slow to be used for realistic geometries. The diffusion equation can be solved quickly for realistic geometries, but is only valid in scattering regions. In this paper we describe experiments carried out on a solid slab phantom to investigate the effect of clear regions. The experimental results were compared with the different models of light propagation. We found that the presence of a clear layer had a significant effect upon the light distribution, which was modelled correctly by Monte Carlo techniques, but not by diffusion theory. A novel approach to calculating the light transport was developed, using diffusion theory to analyze the scattering regions combined with a radiosity approach to analyze the propagation through the clear region. Results from this approach were found to agree with both the Monte Carlo and experimental data.

Mesh:

Year:  1996        PMID: 8730669     DOI: 10.1088/0031-9155/41/4/012

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  18 in total

1.  Visible and near-infrared laser radiation in a biological tissue. A forward model for medical imaging by optical tomography.

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2.  Light transport in turbid media with non-scattering, low-scattering and high absorption heterogeneities based on hybrid simplified spherical harmonics with radiosity model.

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3.  A simulation study of the variability of indocyanine green kinetics and using structural a priori information in dynamic contrast enhanced diffuse optical tomography (DCE-DOT).

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Journal:  Phys Med Biol       Date:  2008-05-27       Impact factor: 3.609

4.  Depth sensitivity analysis of functional near-infrared spectroscopy measurement using three-dimensional Monte Carlo modelling-based magnetic resonance imaging.

Authors:  Chemseddine Mansouri; Jean-Pierre L'huillier; Nasser H Kashou; Anne Humeau
Journal:  Lasers Med Sci       Date:  2010-02-09       Impact factor: 3.161

5.  Image reconstruction in optical tomography.

Authors:  S R Arridge; M Schweiger
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1997-06-29       Impact factor: 6.237

6.  Diffuse Optics for Tissue Monitoring and Tomography.

Authors:  T Durduran; R Choe; W B Baker; A G Yodh
Journal:  Rep Prog Phys       Date:  2010-07

7.  A near infrared spectroscopy study investigating oxygen utilisation in hydrocephalic rats.

Authors:  Zareen Bashir; Jemma Miller; Jaleel Ahmad Miyan; Maureen Susan Thorniley
Journal:  Exp Brain Res       Date:  2006-05-30       Impact factor: 1.972

8.  Numerical simulation of endovenous laser treatment of the incompetent great saphenous vein with external air cooling.

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Journal:  Lasers Med Sci       Date:  2012-07-27       Impact factor: 3.161

Review 9.  Measurements of scattering and absorption changes in muscle and brain.

Authors:  E Gratton; S Fantini; M A Franceschini; G Gratton; M Fabiani
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1997-06-29       Impact factor: 6.237

10.  Photon diffusion near the point-of-entry in anisotropically scattering turbid media.

Authors:  Edward Vitkin; Vladimir Turzhitsky; Le Qiu; Lianyu Guo; Irving Itzkan; Eugene B Hanlon; Lev T Perelman
Journal:  Nat Commun       Date:  2011-12-13       Impact factor: 14.919

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