Literature DB >> 8730381

Incidence of five common fracture types in an institutional epileptic population.

K B Desai1, W J Ribbans, G J Taylor.   

Abstract

We have reviewed 4521 patient-years and analysed 185,066 seizures to calculate the incidence of five common fractures in an epileptic population. Only 25.0 per cent of these fractures were known to have occurred during a seizure. When age and sex matched against a 'normal population', there was an increased incidence of femoral neck fractures (5.2 x), inter-trochanteric fractures (9.9 x), ankle fractures (9.9 x) and proximal humerus fractures (4.2 x). Surprisingly, there was no increased incidence of wrist fractures. Overall, there was a 4.3 x increased risk for all fractures and 3.2 x increased risk of fractures not related to fits. There was no evidence for the first fracture occurring at a younger age in this population. The possible causes of this greatly increased risk are discussed.

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Year:  1996        PMID: 8730381     DOI: 10.1016/0020-1383(95)00189-1

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  14 in total

1.  The Association Between Antiepileptic Drugs and Bone Disease.

Authors:  Alison M. Pack
Journal:  Epilepsy Curr       Date:  2003-05       Impact factor: 7.500

2.  Unusual presentation of altered bone metabolism with long-term antiepileptic therapy: pathological fracture of neck of femur due to brown tumor at calcer.

Authors:  Sumit Kumar Jain; Shuvendu Prosad Roy; Vaibhav Gulati; Onkar Nath Nagi
Journal:  Musculoskelet Surg       Date:  2011-04-21

Review 3.  Adverse effects of antiepileptic drugs on bone structure: epidemiology, mechanisms and therapeutic implications.

Authors:  A M Pack; M J Morrell
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

4.  Spontaneous bilateral neck of femur fractures and shoulder dislocation.

Authors:  Khurram Siddique; Lambros Athanatos; Philip Housden
Journal:  BMJ Case Rep       Date:  2011-01-25

5.  Ilizarov treatment of humeral shaft nonunion in an antiepileptic drug patient with uncontrolled generalized tonic-clonic seizure activity.

Authors:  Vasileios S Sioros; Marios G Lykissas; Dimitrios Pafilas; Panayiotis Koulouvaris; Alexandros N Mavrodontidis
Journal:  J Orthop Surg Res       Date:  2010-07-28       Impact factor: 2.359

6.  Seizure induced polytrauma; not just posterior dislocation of the shoulder.

Authors:  James Ritchie Gill; Colin G Murphy; Benjamin Quansah; Andrew D Carrothers
Journal:  BMJ Case Rep       Date:  2015-08-25

Review 7.  Seizure-related injuries, drowning and vehicular crashes -- a critical review of the literature.

Authors:  Michael Tan; Wendyl D'Souza
Journal:  Curr Neurol Neurosci Rep       Date:  2013-07       Impact factor: 5.081

Review 8.  Bone disease in epilepsy.

Authors:  Alison M Pack
Journal:  Curr Neurol Neurosci Rep       Date:  2004-07       Impact factor: 5.081

9.  Dual-energy X-ray absorptiometry versus quantitative ultrasonography in diagnosing osteoporosis in patients with refractory epilepsy and chronic antiepileptic drug use.

Authors:  Kim Beerhorst; Joost Tan; In Yu Tan; Pauline Verschuure; Albert P Aldenkamp
Journal:  Ther Adv Musculoskelet Dis       Date:  2013-04       Impact factor: 5.346

10.  Antiepileptic drugs and bone metabolism.

Authors:  Helen A Valsamis; Surender K Arora; Barbara Labban; Samy I McFarlane
Journal:  Nutr Metab (Lond)       Date:  2006-09-06       Impact factor: 4.169

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