Literature DB >> 872907

Mobilization of hematopoietic stem cells (CFU-C) into the peripheral blood of man by endotoxin.

M J Cline, D W Golde.   

Abstract

Pseudomonas endotoxin was administered to three normal subjects in order to assess possible effects on stem cell circulation. Increased numbers of granulopoietic stem cells (CFU-C) transiently appeared in the peripheral blood, reaching a maximum after the time of maximal leukopenia. There was a mean 4-fold increase in CFU-C per ml of blood following endotoxin. A high proportion of these CFU-C did not require an added source of colony-stimulating activity for growth in agar.

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Year:  1977        PMID： 872907

Source DB:  PubMed          Journal:  Exp Hematol        ISSN： 0301-472X            Impact factor:   3.084


  13 in total

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9.  Restoration of hemopoiesis by CFU-S from different backgrounds in the mouse.

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10.  Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function.

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