Literature DB >> 872873

Modulation of heroin self-administration by neurohypophyseal principles.

J M Van Ree, D De Wied.   

Abstract

Neuropeptides related to hypothalomic-neurohypophyseal hormones affect intravenous heroin self-administration behavior in rats. Desglycinamide9, arginine8-vasopressin and pressinamide reduced, while oxytocin and its C-terminal tripeptide, prolyl-leucyl-glycinamide facilitated this behavior. The effectiveness of the vasopressin analogue appeared to be of a long term nature. The data indicate a modulating effect of these principles on the reinforcing efficacy of heroin.

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Year:  1977        PMID： 872873     DOI： 10.1016/0014-2999(77)90132-7

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  4 in total

1.  Transport of desglycinamide-arginine vasopressin across the blood-brain barrier in rats as evaluated by the unit impulse response methodology.

Authors:  J B van Bree; S Tio; A G de Boer; M Danhof; J C Verhoef; D D Breimer
Journal:  Pharm Res       Date:  1990-03       Impact factor: 4.200

Review 2.  Oxytocin and opioid addiction revisited: old drug, new applications.

Authors:  Panos Zanos; Polymnia Georgiou; Carol Weber; Fiona Robinson; Christos Kouimtsidis; Ramin Niforooshan; Alexis Bailey
Journal:  Br J Pharmacol       Date:  2017-04-06       Impact factor: 8.739

3.  Oxytocin diminishes heroin tolerance in mice.

Authors:  G L Kovács; M Faludi; G Telegdy
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

Review 4.  Effect of early life social adversity on drug abuse vulnerability: Focus on corticotropin-releasing factor and oxytocin.

Authors:  Michael T Bardo; Lindsey R Hammerslag; Samantha G Malone
Journal:  Neuropharmacology       Date:  2021-04-13       Impact factor: 5.273
  4 in total

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