Literature DB >> 8728611

The prospects for developing a vaccine against Staphylococcus aureus.

J C Lee1.   

Abstract

Staphylococcus aureus is an important bacterial pathogen with multiple virulence factors. The prevalence of antibiotic resistance among clinical isolates means that new vaccine strategies to prevent staphylococcal infections are needed. An ideal vaccine would induce antibodies to prevent bacterial adherence, promote opsonophagocytic killing by leukocytes and neutralize toxic secreted proteins.

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Year:  1996        PMID： 8728611     DOI： 10.1016/0966-842x(96)10021-4

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  15 in total

1.  Synthetic peptide immunogens elicit polyclonal and monoclonal antibodies specific for linear epitopes in the D motifs of Staphylococcus aureus fibronectin-binding protein, which are composed of amino acids that are essential for fibronectin binding.

Authors:  M Huesca; Q Sun; R Peralta; G M Shivji; D N Sauder; M J McGavin
Journal:  Infect Immun       Date:  2000-03       Impact factor: 3.441

2.  Comparative analysis of the roles of HtrA-like surface proteases in two virulent Staphylococcus aureus strains.

Authors:  Candice Rigoulay; José M Entenza; David Halpern; Eleonora Widmer; Philippe Moreillon; Isabelle Poquet; Alexandra Gruss
Journal:  Infect Immun       Date:  2005-01       Impact factor: 3.441

3.  A mutant of staphylococcal enterotoxin C devoid of bacterial superantigenic activity elicits a Th2 immune response for protection against Staphylococcus aureus infection.

Authors:  Dong-Liang Hu; Jing-Chun Cui; Katsuhiko Omoe; Hiroshi Sashinami; Yuichi Yokomizo; Kunihiro Shinagawa; Akio Nakane
Journal:  Infect Immun       Date:  2005-01       Impact factor: 3.441

4.  Protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide in a modified model of endocarditis in rats.

Authors:  J C Lee; J S Park; S E Shepherd; V Carey; A Fattom
Journal:  Infect Immun       Date:  1997-10       Impact factor: 3.441

Review 5.  Progress in the development of effective vaccines to prevent selected gram-positive bacterial infections.

Authors:  Michael S Bronze; James B Dale
Journal:  Am J Med Sci       Date:  2010-09       Impact factor: 2.378

Review 6.  [Postoperative and bacterial osteitis. New possibilities for therapy].

Authors:  V Heppert; U Glatzel; A Wentzensen
Journal:  Orthopade       Date:  2004-03       Impact factor: 1.087

7.  Proteomics-based identification of anchorless cell wall proteins as vaccine candidates against Staphylococcus aureus.

Authors:  Eva Glowalla; Bettina Tosetti; Martin Krönke; Oleg Krut
Journal:  Infect Immun       Date:  2009-04-13       Impact factor: 3.441

8.  Vaccination with a recombinant fragment of collagen adhesin provides protection against Staphylococcus aureus-mediated septic death.

Authors:  I M Nilsson; J M Patti; T Bremell; M Höök; A Tarkowski
Journal:  J Clin Invest       Date:  1998-06-15       Impact factor: 14.808

9.  Selection and characterization of murine monoclonal antibodies to Staphylococcus aureus iron-regulated surface determinant B with functional activity in vitro and in vivo.

Authors:  Martha Brown; Rose Kowalski; Julie Zorman; Xin-Min Wang; Victoria Towne; Qinjian Zhao; Susan Secore; Adam C Finnefrock; Tim Ebert; Greg Pancari; Kevin Isett; Yuhua Zhang; Annaliesa S Anderson; Donna Montgomery; Leslie Cope; Tessie McNeely
Journal:  Clin Vaccine Immunol       Date:  2009-06-24

10.  Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model.

Authors:  Amita Joshi; Greg Pancari; Leslie Cope; Edward P Bowman; Daniel Cua; Richard A Proctor; Tessie McNeely
Journal:  Hum Vaccin Immunother       Date:  2012-02-13       Impact factor: 3.452
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