Literature DB >> 8728111

EGF receptor in human Chang liver and hepatoma HepG2 cells.

E B Yang1, D F Wang, P Mack, L Y Cheng.   

Abstract

Epidermal growth factor (EGF) receptor was detected in the human Chang liver and human hepatoma HepG2 cells. Both cell lines were found to be able to bind EGF. The expression of EGF receptor in Chang liver and HepG2 cells was 1.3 x 10(5) EGF receptors/cell and 1.8 x 10(5) EGF receptors/cell, respectively. In both cells, this receptor was identified by ECL Western blotting using monoclonal anti-EGF receptor antibody and by immunohistochemical assay using polyclonal anti-EGF receptor antibody. Some of internalized EGF was recycled in Chang liver cells, but not in HepG2 cells.

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Year:  1996        PMID: 8728111

Source DB:  PubMed          Journal:  Biochem Mol Biol Int        ISSN: 1039-9712


  2 in total

1.  Downregulation of galectin-3 by EGF mediates the apoptosis of HepG2 cells.

Authors:  Zhenzhen Hu; Xiuqin Jiang; Ying Xu; Nan Lu; Weizhi Wang; Jie Luo; Han Zou; Datong Zheng; Xing Feng
Journal:  Mol Cell Biochem       Date:  2012-07-04       Impact factor: 3.396

2.  Insulin suppresses transcriptional activity of yes-associated protein in insulin target cells.

Authors:  Samar Sayedyahossein; Andrew C Hedman; David B Sacks
Journal:  Mol Biol Cell       Date:  2019-11-06       Impact factor: 4.138

  2 in total

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