[The role of the cholinergic system of the brain in the mechanisms of dissociated learning].

The mechanisms of dissociated learning in rats were studied with application on conditioning technique and pharmacological analysis of memory. Anticholinesterase drugs were shown to be interchangeable in inducing dissociated states in learning. Anticholinergic substances completely neutralized the ability of cholinergic drugs that create dissociated states. It was shown that muscarinic cholinergic receptors largely contribute in inducing dissociated states. The findings well agree with the earlier author's hypothesis that the cholinergic brain system plays a decisive role in the mechanisms of dissociated learning.