Literature DB >> 8725940

Mechanism of V(D)J recombination.

M Bogue1, D B Roth.   

Abstract

V(D)J recombination can be separated into two basic operations: DNA cleavage and joining of broken ends. Our understanding of both reactions has increased substantially in the past year. Major advances include the development of a cell-free system capable of cleavage and the identification of several proteins involved in both V(D)J recombination and double-strand break repair.

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Year:  1996        PMID： 8725940     DOI： 10.1016/s0952-7915(96)80055-0

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  22 in total

1.  The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2.

Authors:  V Aidinis; T Bonaldi; M Beltrame; S Santagata; M E Bianchi; E Spanopoulou
Journal:  Mol Cell Biol       Date:  1999-10       Impact factor: 4.272

Review 2.  The RAG proteins in V(D)J recombination: more than just a nuclease.

Authors:  M J Sadofsky
Journal:  Nucleic Acids Res       Date:  2001-04-01       Impact factor: 16.971

3.  Timing of developmentally programmed excision and circularization of Paramecium internal eliminated sequences.

Authors:  M Bétermier; S Duharcourt; H Seitz; E Meyer
Journal:  Mol Cell Biol       Date:  2000-03       Impact factor: 4.272

Review 4.  Immunodeficiency associated with DNA repair defects.

Authors:  A R Gennery; A J Cant; P A Jeggo
Journal:  Clin Exp Immunol       Date:  2000-07       Impact factor: 4.330

5.  Inverse transposition by the RAG1 and RAG2 proteins: role reversal of donor and target DNA.

Authors:  I-hung Shih; Meni Melek; Nadeesha D Jayaratne; Martin Gellert
Journal:  EMBO J       Date:  2002-12-02       Impact factor: 11.598

Review 6.  Reversing T cell immunosenescence: why, who, and how.

Authors:  Pierre Olivier Lang; Sheila Govind; Richard Aspinall
Journal:  Age (Dordr)       Date:  2012-02-26

7.  Definition of a T-cell receptor beta gene core enhancer of V(D)J recombination by transgenic mapping.

Authors:  R K Tripathi; N Mathieu; S Spicuglia; D Payet; C Verthuy; G Bouvier; D Depetris; M G Mattei; W M HempeL; P Ferrier
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

8.  Gene discovery at the human T-cell receptor alpha/delta locus.

Authors:  Marsha R Haynes; Gillian E Wu
Journal:  Immunogenetics       Date:  2006-12-13       Impact factor: 2.846

9.  V(D)J recombination intermediates and non-standard products in XRCC4-deficient cells.

Authors:  J O Han; L A Erskine; M M Purugganan; T D Stamato; D B Roth
Journal:  Nucleic Acids Res       Date:  1998-08-15       Impact factor: 16.971

10.  Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining.

Authors:  W M Hempel; P Stanhope-Baker; N Mathieu; F Huang; M S Schlissel; P Ferrier
Journal:  Genes Dev       Date:  1998-08-01       Impact factor: 11.361
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