Literature DB >> 8725113

Analysis of the nucleotide sequence of 23.8 kbp from the left terminus of the genome of variola major virus strain India-1967.

S N Shchelkunov1, A V Totmenin, L S Sandakhchiev.   

Abstract

Sequencing and computer analysis of the nucleotide sequence of variola major virus strain India-1967 (VAR-IND) DNA segment (23 786 bp) covering the left variable region of the viral genome has been carried out. Twenty-nine potential open reading frames were identified. Structure-function organization of the VAR-IND DNA segment was compared with previously reported sequences from analogous genome regions of vaccinia virus strains Copenhagen (VAC-COP) and Western Reserve (VAC-WR). Multiple structural differences between the VAR-IND and genome regions were analysed and both VAC-COP and VAC-WR have been found. Possible molecular factors of virulence, virus host range genes as well as differences revealed in the structure of these genes of VAR and VAC will be discussed.

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Year:  1996        PMID： 8725113     DOI： 10.1016/0168-1702(95)01269-9

Source DB:  PubMed          Journal:  Virus Res        ISSN： 0168-1702            Impact factor:   3.303


  10 in total

1.  Species-specific differences in the organization of the complement-binding protein of orthopoxviruses.

Authors:  S N Shchelkunov; E A Uvarova; A V Totmenin; P F Safronov; L S Sandakhchiev
Journal:  Dokl Biochem Biophys       Date:  2001 Jul-Aug       Impact factor: 0.788

2.  Extensive gene gain associated with adaptive evolution of poxviruses.

Authors:  Aoife McLysaght; Pierre F Baldi; Brandon S Gaut
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-05       Impact factor: 11.205

3.  Poxvirus orthologous clusters: toward defining the minimum essential poxvirus genome.

Authors:  Chris Upton; Stephanie Slack; Arwen L Hunter; Angelika Ehlers; Rachel L Roper
Journal:  J Virol       Date:  2003-07       Impact factor: 5.103

4.  Characterization of the vaccinia virus A35R protein and its role in virulence.

Authors:  Rachel L Roper
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

Review 5.  Smallpox: gone but not forgotten.

Authors:  P D Ellner
Journal:  Infection       Date:  1998 Sep-Oct       Impact factor: 3.553

6.  MHC-I-restricted epitopes conserved among variola and other related orthopoxviruses are recognized by T cells 30 years after vaccination.

Authors:  S T Tang; M Wang; K Lamberth; M Harndahl; M H Dziegiel; M H Claesson; S Buus; O Lund
Journal:  Arch Virol       Date:  2008-09-12       Impact factor: 2.574

Review 7.  Interaction of orthopoxviruses with the cellular ubiquitin-ligase system.

Authors:  Sergei N Shchelkunov
Journal:  Virus Genes       Date:  2010-08-12       Impact factor: 2.198

8.  PSPP: a protein structure prediction pipeline for computing clusters.

Authors:  Michael S Lee; Rajkumar Bondugula; Valmik Desai; Nela Zavaljevski; In-Chul Yeh; Anders Wallqvist; Jaques Reifman
Journal:  PLoS One       Date:  2009-07-16       Impact factor: 3.240

9.  Genome Sequences of Akhmeta Virus, an Early Divergent Old World Orthopoxvirus.

Authors:  Jinxin Gao; Crystal Gigante; Ekaterine Khmaladze; Pengbo Liu; Shiyuyun Tang; Kimberly Wilkins; Kun Zhao; Whitni Davidson; Yoshinori Nakazawa; Giorgi Maghlakelidze; Marika Geleishvili; Maka Kokhreidze; Darin S Carroll; Ginny Emerson; Yu Li
Journal:  Viruses       Date:  2018-05-12       Impact factor: 5.048

10.  Variola virus genome sequenced from an eighteenth-century museum specimen supports the recent origin of smallpox.

Authors:  Giada Ferrari; Judith Neukamm; Helle T Baalsrud; Abagail M Breidenstein; Mark Ravinet; Carina Phillips; Frank Rühli; Abigail Bouwman; Verena J Schuenemann
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2020-10-05       Impact factor: 6.237
  10 in total

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