| Literature DB >> 872377 |
R H Smith, J A MacDonald, D S Thompson, W E Flacke.
Abstract
We describe an isothermal gas-liquid chromatographic procedure developed for measuring thiamylal and thiopental in plasma. The unchanged drug is extracted into ethyl acetate from acidified plasma, together with an internal standard. The solvent is removed, the residue methylated, aliquots, diluted with benzene, are injected into a 183-cm gas-liquid chromatographic column containing 3% OV-17. Sensitivity of detection is in the nanogram to picogram range.Entities:
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Year: 1977 PMID： 872377
Source DB: PubMed Journal: Clin Chem ISSN： 0009-9147 Impact factor: 8.327