Literature DB >> 872309

The extraction of thallium-201 by the myocardium.

H F Weich, H W Strauss, B Pitt.   

Abstract

The concentration of thallium-201 in the myocardium immediately following injection of tracer is the result of both blood flow delivering tracer to the heart and extraction by the myocardium. In these studies, the extraction of thallium-201 by the canine myocardium was determined as a function of heart rate, coronary blood flow, hypoxia, changes in pH, and following administration of propranolol, insulin, and strophanthin. Under basal conditions, extraction fraction measured 88 +/- 2.1%, following pacing to a rate of 195 beats/min extraction fraction remained unchanged at 88.5%. Similar results were found with changes in pH, propranolol, insulin, and strophanthin. Hypoxia caused a significant decrease in extraction fraction to 77.9%. When coronary blood flow was increased in excess of demands by drugs, extraction fraction fell logarithmically.

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Year:  1977        PMID： 872309     DOI： 10.1161/01.cir.56.2.188

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


  44 in total

1.  The challenge of quantifying defect size and severity: reality versus algorithm.

Authors:  R L Eisner; R E Patterson
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Review 2.  Comparison of Tl-201 with Tc-99m-labeled myocardial perfusion agents: technical, physiologic, and clinical issues.

Authors:  P Kailasnath; A J Sinusas
Journal:  J Nucl Cardiol       Date:  2001 Jul-Aug       Impact factor: 5.952

Review 3.  Myocardial perfusion imaging agents: SPECT and PET.

Authors:  George A Beller; Steven R Bergmann
Journal:  J Nucl Cardiol       Date:  2004 Jan-Feb       Impact factor: 5.952

Review 4.  Quantitative assessment of regional myocardial blood flow with thallium-201 and SPECT.

Authors:  H Iida; S Eberl
Journal:  J Nucl Cardiol       Date:  1998 May-Jun       Impact factor: 5.952

5.  Applying coronary physiology for the nuclear cardiologist: new observations from intracoronary flow velocity and reserve in patients.

Authors:  M J Kern
Journal:  J Nucl Cardiol       Date:  1994 Nov-Dec       Impact factor: 5.952

6.  Quantitative evaluation of manganese-52m as a myocardial perfusion tracer in pigs using positron emission tomography.

Authors:  A Buck; N Nguyen; C Burger; S Ziegler; L Frey; G Weigand; W Erhardt; R Senekowitsch-Schmidtke; R Pellikka; P Bläuenstein; J T Locher; M Schwaiger
Journal:  Eur J Nucl Med       Date:  1996-12

7.  Effect of glucose and insulin infusion on the myocardial extraction of a radioiodinated methyl-substituted fatty acid.

Authors:  J A Bianco; D R Elmaleh; J A Leppo; M A King; A Moring; E Livni; E Espinoza; J S Alpert; H W Strauss
Journal:  Eur J Nucl Med       Date:  1986

8.  Absolute quantitation of myocardial blood flow with (201)Tl and dynamic SPECT in canine: optimisation and validation of kinetic modelling.

Authors:  Hidehiro Iida; Stefan Eberl; Kyeong-Min Kim; Yoshikazu Tamura; Yukihiko Ono; Mayumi Nakazawa; Antti Sohlberg; Tsutomu Zeniya; Takuya Hayashi; Hiroshi Watabe
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-01-15       Impact factor: 9.236

9.  Defect reversibility using thallium-201 reinjection. Comparison of stress-redistribution-reinjection with stress-immediate reinjection.

Authors:  B L van Eck-Smit; A F Kuijper; A H Zwinderman; A V Bruschke; E K Pauwels; E E van der Wall
Journal:  Int J Card Imaging       Date:  1996-03

10.  Long-term prognostic value of stress-redistribution-reinjection Tl-201 imaging in patients with severe left ventricular dysfunction and coronary artery bypass surgery.

Authors:  Metin Gürsürer; Ayşe Emre; Hakan Gerçekoğlu; Seyfi Uslubaş; Mehmet Aksoy; Birsen Ersek
Journal:  Int J Cardiovasc Imaging       Date:  2002-04       Impact factor: 2.357
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