Literature DB >> 8721446

Small-diameter invasive melanomas: clinical and pathologic characteristics.

A Gonzalez1, A J West, J V Pitha, J W Taira.   

Abstract

BACKGROUND: Most melanomas when first diagnosed clinically are larger than common benign melanocytic nevi ( > 6 mm). Smaller melanomas, however, may occasionally occur. Yet, very little is known about them.
OBJECTIVE: To determine the incidence and delineate the clinical and histologic characteristics of small-diameter invasive melanomas.
METHODS: Slides of all melanomas diagnosed between 1984-1993 were reviewed and measured. All invasive lesions less than 6 mm were further scrutinized clinically and morphologically.
RESULTS: Among 357 invasive melanomas, 16 (4.4%) were less than 6 mm. Most lesions lacked some of the histologic features usually seen in large melanomas. One half of them were over 0.75 mm deep. Patients with small melanomas were on average 15 years younger than those with large lesions. In females, sites on the upper extremities predominate. In females, small melanomas had clinical signs of melanoma, while in males they resembled nevi.
CONCLUSION: Melanomas smaller than 6 mm are not rare. Clinicians and pathologists must learn their features in order to diagnose them properly.

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Mesh:

Year:  1996        PMID: 8721446     DOI: 10.1111/j.1600-0560.1996.tb01285.x

Source DB:  PubMed          Journal:  J Cutan Pathol        ISSN: 0303-6987            Impact factor:   1.587


  4 in total

1.  Histopathological characteristics of small diameter melanocytic naevi.

Authors:  M Braun-Falco; R Hein; J Ring; N S McNutt
Journal:  J Clin Pathol       Date:  2003-06       Impact factor: 3.411

2.  Melanocytic lesions ≤ 6mm: Prospective series of 481 melanocytic trunk and limb lesions in Brazil.

Authors:  Gabriella Campos-do-Carmo; Aretha Brito Nobre; Tullia Cuzzi; Giuseppe Argenziano; Carlos Gil Ferreira; Luiz Claudio Santos Thuler
Journal:  PLoS One       Date:  2021-06-08       Impact factor: 3.240

3.  Micromelanomas: A Review of Melanomas ≤2 mm and a Case Report.

Authors:  Sharad P Paul
Journal:  Case Rep Oncol Med       Date:  2014-01-19

4.  The role of dermoscopy and digital dermoscopy follow-up in the clinical diagnosis of melanoma: clinical and dermoscopic features of 99 consecutive primary melanomas.

Authors:  Gabriel Salerni; Teresita Terán; Carlos Alonso; Ramón Fernández-Bussy
Journal:  Dermatol Pract Concept       Date:  2014-10-31
  4 in total

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