Literature DB >> 8721430

Fatal cerebellar haemorrhage due to phenprocoumon poisoning.

T Höhler1, J Becker, K H Meyer zum Büschenfelde, C Rittner.   

Abstract

A 32-year-old patient died of a cerebellar haemorrhage and the blood coagulation analysis before death suggested defective synthesis of vitamin K-dependent clotting factors due to vitamin K deficiency. The post-mortem toxicological examination of different tissues revealed phenprocoumon poisoning as the cause of death. The differential diagnosis of vitamin K deficiency and the toxicology of hydroxycoumarins are discussed.

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Year:  1996        PMID: 8721430     DOI: 10.1007/BF01369825

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  11 in total

1.  HAEMORRHAGIC DIATHESIS DUE TO CRIMINAL POISONING WITH WARFARIN.

Authors:  E IKKALA; G MYLLYLAE; H R NEVANLINNA; R PELKONEN; K PYOERAELAE
Journal:  Acta Med Scand       Date:  1964-08

2.  Hypoprothrombinemia due to dicumarol in a malingerer: a case report.

Authors:  W A STAFNE; A E MOE
Journal:  Ann Intern Med       Date:  1951-10       Impact factor: 25.391

3.  Suicide attempt with warfarin, a bishydroxycoumarin-like rodenticide.

Authors:  R W HOLMES; J LOVE
Journal:  J Am Med Assoc       Date:  1952-03-15

Review 4.  Vitamin K.

Authors:  M J Shearer
Journal:  Lancet       Date:  1995-01-28       Impact factor: 79.321

5.  Toxicological case records.

Authors:  R Goulding
Journal:  Practitioner       Date:  1968-02

6.  [Acute liver cell degeneration with hepatorenal syndrome in monocoumarolin intoxication].

Authors:  U Stark; G Zalaudek; H Samec; H Sterz
Journal:  Wien Med Wochenschr       Date:  1971-04-24

7.  [Attempted murder with phenprocoumon (marcumar)(author's transl)].

Authors:  W Schneider; G Girmann; R Luthe; H J Wagner
Journal:  Dtsch Med Wochenschr       Date:  1975-09-12       Impact factor: 0.628

8.  Drug-induced hepatitis: a rare complication of oral anticoagulants.

Authors:  T Höhler; M Schnütgen; I Helmreich-Becker; W J Mayet; K H Mayer zum Büschenfelde
Journal:  J Hepatol       Date:  1994-09       Impact factor: 25.083

9.  Comparative acute oral toxicity of sodium warfarin and microcrystalline warfarin in the Sprague-Dawley rat.

Authors:  N Back; R Steger; J M Glassman
Journal:  Pharmacol Res Commun       Date:  1978-05

10.  [Observations in phenprocoumon (Marcumar) poisoning. Elimination and serum binding of the anticoagulant atatoxic blood concentration].

Authors:  H Held; G von Busse; J Meissner
Journal:  Dtsch Med Wochenschr       Date:  1980-06-13       Impact factor: 0.628

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