S Kokubun1, H Ozawa, M Sakurai, Y Tanaka. 1. Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan.
Abstract
STUDY DESIGN: An elderly women with tumoral calcinosis between the C1 posterior arch and the C2 lamina is reported. OBJECTIVES: To describe a rare occurrence of tumoral calcinosis in the spine and discuss its pathomechanism. SUMMARY OF BACKGROUND DATA: Tumoral calcinosis is a rare condition occurring predominantly in the juxtaarticular regions of the extremities. Involvement of the spine has been reported in only one case in the lumbar spine. The calcium phosphate crystals that have been identified are those of hydroxyapatite. METHODS: The calcified material was removed, and its crystalline phase was analyzed. RESULTS: Neck pain was relieved by removal of the calcified material. Scanning electron microscopy and energy-dispersive x-ray microanalysis revealed that the material consisted of crystals of calcium pyrophosphate dihydrate. CONCLUSIONS: Tumoral calcinosis should be included among the clinical presentations of calcium pyrophosphate dihydrate crystal deposition disease.
STUDY DESIGN: An elderly women with tumoral calcinosis between the C1 posterior arch and the C2 lamina is reported. OBJECTIVES: To describe a rare occurrence of tumoral calcinosis in the spine and discuss its pathomechanism. SUMMARY OF BACKGROUND DATA: Tumoral calcinosis is a rare condition occurring predominantly in the juxtaarticular regions of the extremities. Involvement of the spine has been reported in only one case in the lumbar spine. The calcium phosphate crystals that have been identified are those of hydroxyapatite. METHODS: The calcified material was removed, and its crystalline phase was analyzed. RESULTS:Neck pain was relieved by removal of the calcified material. Scanning electron microscopy and energy-dispersive x-ray microanalysis revealed that the material consisted of crystals of calcium pyrophosphate dihydrate. CONCLUSIONS:Tumoral calcinosis should be included among the clinical presentations of calcium pyrophosphate dihydratecrystal deposition disease.
Authors: John D Young; Jan Martel; David Young; Andrew Young; Chin-Ming Hung; Lena Young; Ying-Jie Chao; James Young; Cheng-Yeu Wu Journal: PLoS One Date: 2009-05-01 Impact factor: 3.240