Literature DB >> 8720394

Ginsenoside Rh4, a genuine dammarane glycoside from Korean red ginseng.

N I Baek1, D S Kim, Y H Lee, J D Park, C B Lee, S I Kim.   

Abstract

A genuine glycoside, named ginsenoside Rh4, was isolated from Korean red ginseng (Panax ginseng C. A. Meyer) through repeated column chromatography, and its chemical structure was established to be 6-O-beta-D-glucopyranosyldammar-20(22),24-diene-3 beta,6 alpha,12 beta-triol by spectral and chemical methods. The stereochemistry of a double bond at C-20(22) of ginsenoside Rh4 was characterized as (E) from a NOESY experiment in the 1H-NMR of the aglycone. Cytotoxic activities of ginsenoside Rh4 and its aglycone against cancer cell lines were evaluated by use of the SRB method.

Entities:  

Mesh:

Substances:

Year:  1996        PMID: 8720394     DOI: 10.1055/s-2006-957816

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  30 in total

1.  Immunostimulation activity of a polysaccharide from fermented ginseng with Hericium erinaceum mycelia in solid-state culture.

Authors:  Hoon Kim; Hyung-Joo Suh; Ki-Han Kwon; Jong-Hyun Hwang; Kwang-Won Yu
Journal:  Food Sci Biotechnol       Date:  2016-02-29       Impact factor: 2.391

2.  Skin anti-photoaging properties of ginsenoside Rh2 epimers in UV-B-irradiated human keratinocyte cells.

Authors:  Sun-Joo Oh; Sihyeong Lee; Woo-Yong Choi; Chang-Jin Lim
Journal:  J Biosci       Date:  2014-09       Impact factor: 1.826

3.  Changes of [3H]MK-801, [3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of transformed ginsenosides.

Authors:  Soyong Jang; Jong Hoon Ryu; Dong-Hyun Kim; Seikwan Oh
Journal:  Neurochem Res       Date:  2004-12       Impact factor: 3.996

4.  Three new triterpenoids from Panax ginseng exhibit cytotoxicity against human A549 and Hep-3B cell lines.

Authors:  Hai-Ying Ma; Hui-Yuan Gao; Jian Huang; Bo-Hang Sun; Bo Yang
Journal:  J Nat Med       Date:  2012-04-12       Impact factor: 2.343

5.  Korean red ginseng protects against neuronal damage induced by transient focal ischemia in rats.

Authors:  Ju Yeon Ban; Sung Wook Kang; Jong Seok Lee; Joo-Ho Chung; Young Gwan Ko; Han Sung Choi
Journal:  Exp Ther Med       Date:  2012-01-11       Impact factor: 2.447

6.  Effects of Red Liriope platyphylla on NGF secretion ability, NGF receptor signaling pathway and γ-secretase components in NSE/hAPPsw transgenic mice expressing Alzheimer's Disease.

Authors:  Sun-Il Choi; Jun-Seo Goo; Ji-Eun Kim; In-Sik Hwang; Hye-Ryun Lee; Young-Ju Lee; Hong-Joo Son; Hee-Seob Lee; Jong-Sup Lee; Dae-Youn Hwang
Journal:  Lab Anim Res       Date:  2012-09-26

7.  Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng.

Authors:  Dong-Hyun Kim
Journal:  J Ginseng Res       Date:  2012-01       Impact factor: 6.060

8.  Inhibition of TNF-α-mediated NF-κB Transcriptional Activity in HepG2 Cells by Dammarane-type Saponins from Panax ginseng Leaves.

Authors:  Seok Bean Song; Nguyen Huu Tung; Tran Hong Quang; Nguyen Thi Thanh Ngan; Kyoon Eon Kim; Young Ho Kim
Journal:  J Ginseng Res       Date:  2012-04       Impact factor: 6.060

9.  Toxicity of red Liriope platyphylla manufactured by steaming process on liver and kidney organs of ICR mice.

Authors:  Sun-Il Choi; Ji-Eun Kim; In-Sik Hwang; Hye-Ryun Lee; Young-Ju Lee; Moon-Hwa Kwak; Hong-Joo Son; Hee-Seob Lee; Jong-Sub Lee; Byeong-Cheol Kang; Dae-Youn Hwang
Journal:  Lab Anim Res       Date:  2012-12-26

10.  Effects of Korean Red Ginseng on Cognitive and Motor Function: A Double-blind, Randomized, Placebo-controlled Trial.

Authors:  Hye-Bin Yeo; Ho-Kyoung Yoon; Heon-Jeong Lee; Seung-Gul Kang; Ki-Young Jung; Leen Kim
Journal:  J Ginseng Res       Date:  2012-04       Impact factor: 6.060

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.