| Literature DB >> 8720387 |
S F Horsten1, A J van den Berg, J J Kettenes-van den Bosch, B R Leeflang, R P Labadie.
Abstract
From the latex of Jatropha gossypifolia L. (Euphorbiaceae) a novel cyclic heptapeptide was isolated, which we named cyclogossine A. A combination of amino acid analysis, FAB mass spectrometry, and two dimensional 1H-NMR spectroscopy (TOCSY and ROESY) was used to determine the primary structure. The compound was found to contain one glycine, one alanine, one valine, two leucine, one threonine, and one tryptophan residue; its amino acid sequence is: Leu 1 - Ala 2 - Thr 3 - Trp 4 - Leu 5 - Gly 6 - Val 7. The absolute configurations of the amino acids were determined by chiral gas chromatography; all have the L-configuration.Entities:
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Year: 1996 PMID: 8720387 DOI: 10.1055/s-2006-957795
Source DB: PubMed Journal: Planta Med ISSN: 0032-0943 Impact factor: 3.352