Literature DB >> 8719708

NMDA receptor antagonist MK-801 down-regulates rat striatal proenkephalin and protachykinin mRNAs.

F Zhang1, L Van Bree, N Albala, M Verslype, J J Vanderhaeghen.   

Abstract

Using quantitative in situ hybridization, a significant decrease in expression of proenkephalin (27.1%) and of protachykinin mRNAs (20.0%) is observed in the rat caudate-putamen 14 days after daily intraperitoneal administration of N-methyl-D-aspartate receptor antagonist MK-801, 2 mg/kg.

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Year:  1996        PMID: 8719708     DOI: 10.1016/0197-0186(95)00070-4

Source DB:  PubMed          Journal:  Neurochem Int        ISSN: 0197-0186            Impact factor:   3.921


  1 in total

1.  Dorsal horn-enriched genes identified by DNA microarray, in situ hybridization and immunohistochemistry.

Authors:  Hong Sun; Jian Xu; Kimberly B Della Penna; Robert J Benz; Fumi Kinose; Daniel J Holder; Kenneth S Koblan; David L Gerhold; Hao Wang
Journal:  BMC Neurosci       Date:  2002-08-20       Impact factor: 3.288

  1 in total

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