Literature DB >> 8717059

Heteroplasmy in the control region of human mitochondrial DNA.

D Comas1, S Pääbo, J Bertranpetit.   

Abstract

The sequencing of a 360-nucleotide segment of the mt DNA control region in a population survey revealed the presence of one individual having heteroplasmy in positions 16,293 (A and G) and 16,311 (C and T). This case indicates that heteroplasmy in humans may not be as rare as generally believed.

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Year:  1995        PMID： 8717059     DOI： 10.1101/gr.5.1.89

Source DB:  PubMed          Journal:  Genome Res        ISSN： 1088-9051            Impact factor:   9.043


  23 in total

1.  The frequency of heteroplasmy in the HVII region of mtDNA differs across tissue types and increases with age.

Authors:  C D Calloway; R L Reynolds; G L Herrin; W W Anderson
Journal:  Am J Hum Genet       Date:  2000-03-17       Impact factor: 11.025

2.  A sensitive denaturing gradient-Gel electrophoresis assay reveals a high frequency of heteroplasmy in hypervariable region 1 of the human mtDNA control region.

Authors:  L A Tully; T J Parsons; R J Steighner; M M Holland; M A Marino; V L Prenger
Journal:  Am J Hum Genet       Date:  2000-06-28       Impact factor: 11.025

3.  Hypervariable sites in the mtDNA control region are mutational hotspots.

Authors:  M Stoneking
Journal:  Am J Hum Genet       Date:  2000-08-30       Impact factor: 11.025

4.  A new database of mitochondrial DNA hypervariable regions I and II sequences from 162 Japanese individuals.

Authors:  K Imaizumi; T J Parsons; M Yoshino; M M Holland
Journal:  Int J Legal Med       Date:  2002-04       Impact factor: 2.686

5.  Frequency and pattern of heteroplasmy in the control region of human mitochondrial DNA.

Authors:  Cristina Santos; Blanca Sierra; Luis Alvarez; Amanda Ramos; Elisabet Fernández; Ramón Nogués; Maria Pilar Aluja
Journal:  J Mol Evol       Date:  2008-07-11       Impact factor: 2.395

6.  The occurrence of mtDNA heteroplasmy in multiple cetacean species.

Authors:  Nicole L Vollmer; Amélia Viricel; Lynsey Wilcox; M Katherine Moore; Patricia E Rosel
Journal:  Curr Genet       Date:  2011-01-14       Impact factor: 3.886

7.  Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome.

Authors:  M J Rieder; S L Taylor; V O Tobe; D A Nickerson
Journal:  Nucleic Acids Res       Date:  1998-02-15       Impact factor: 16.971

8.  How rapidly does the human mitochondrial genome evolve?

Authors:  N Howell; I Kubacka; D A Mackey
Journal:  Am J Hum Genet       Date:  1996-09       Impact factor: 11.025

9.  The retrieval of ancient human DNA sequences.

Authors:  O Handt; M Krings; R H Ward; S Pääbo
Journal:  Am J Hum Genet       Date:  1996-08       Impact factor: 11.025

10.  Mutational hot spots in the mitochondrial microcosm.

Authors:  S Pääbo
Journal:  Am J Hum Genet       Date:  1996-09       Impact factor: 11.025
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