Literature DB >> 8713137

zhx-1: a novel mouse homeodomain protein containing two zinc-fingers and five homeodomains.

I Barthelemy1, L Carramolino, J Gutiérrez, J L Barbero, G Márquez, A Zaballos.   

Abstract

A cDNA encoding the complete reading frame of a novel homeodomain-containing protein, named zhx-1, has been cloned from a mouse bone marrow stromal cell line. The ORF encodes a protein of 873 amino acids, in which two C2-H2 zinc-fingers and five homeodomains have been identified. These features classify zhx-1 as a member of the ZF class of homeodomain transcription factors, zhx-1 mRNA is widely expressed in adult mouse, although it is preferentially expressed in brain. At least, two homologous mRNAs are present in humans suggesting that zhx-1 is the first member of a novel subclass of homeodomain factors.

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Year:  1996        PMID: 8713137     DOI: 10.1006/bbrc.1996.1114

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  19 in total

1.  The AT-hook protein D1 is essential for Drosophila melanogaster development and is implicated in position-effect variegation.

Authors:  Nathalie Aulner; Caroline Monod; Guillaume Mandicourt; Denis Jullien; Olivier Cuvier; Alhousseynou Sall; Sam Janssen; Ulrich K Laemmli; Emmanuel Käs
Journal:  Mol Cell Biol       Date:  2002-02       Impact factor: 4.272

2.  Zinc fingers and homeoboxes 2 inhibits hepatocellular carcinoma cell proliferation and represses expression of Cyclins A and E.

Authors:  Xuetian Yue; Zhenyu Zhang; Xiaohong Liang; Lifen Gao; Xiaoning Zhang; Di Zhao; Xiao Liu; Hongxin Ma; Min Guo; Brett T Spear; Yaoqin Gong; Chunhong Ma
Journal:  Gastroenterology       Date:  2012-03-06       Impact factor: 22.682

3.  Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor.

Authors:  Hiroko Kawata; Kazuya Yamada; Zhangfei Shou; Tetsuya Mizutani; Takashi Yazawa; Miki Yoshino; Toshio Sekiguchi; Takashi Kajitani; Kaoru Miyamoto
Journal:  Biochem J       Date:  2003-08-01       Impact factor: 3.857

Review 4.  Zinc fingers and homeoboxes family in human diseases.

Authors:  Y Liu; D Ma; C Ji
Journal:  Cancer Gene Ther       Date:  2015-04-10       Impact factor: 5.987

Review 5.  Zhx2 and Zbtb20: novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer.

Authors:  Martha L Peterson; Chunhong Ma; Brett T Spear
Journal:  Semin Cancer Biol       Date:  2011-01-07       Impact factor: 15.707

6.  Hereditary persistence of alpha-fetoprotein and H19 expression in liver of BALB/cJ mice is due to a retrovirus insertion in the Zhx2 gene.

Authors:  Sudhir Perincheri; R W Cameron Dingle; Martha L Peterson; Brett T Spear
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-30       Impact factor: 11.205

7.  ZHX2 Interacts with Ephrin-B and regulates neural progenitor maintenance in the developing cerebral cortex.

Authors:  Chen Wu; Runxiang Qiu; Jun Wang; Heying Zhang; Kiyohito Murai; Qiang Lu
Journal:  J Neurosci       Date:  2009-06-10       Impact factor: 6.167

8.  Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains.

Authors:  Louise E Bird; Jingshan Ren; Joanne E Nettleship; Gert E Folkers; Raymond J Owens; David K Stammers
Journal:  BMC Struct Biol       Date:  2010-05-28

9.  Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3.

Authors:  Kazuya Yamada; Hiroko Kawata; Zhangfei Shou; Satoko Hirano; Tetsuya Mizutani; Takashi Yazawa; Toshio Sekiguchi; Miki Yoshino; Takashi Kajitani; Kaoru Miyamoto
Journal:  Biochem J       Date:  2003-07-01       Impact factor: 3.857

10.  Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma.

Authors:  Stefan Nagel; Stefan Ehrentraut; Corinna Meyer; Maren Kaufmann; Hans G Drexler; Roderick A F MacLeod
Journal:  PLoS One       Date:  2015-09-25       Impact factor: 3.240

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